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National Collaborating Centre for Women's and Children's Health (UK). Surgical Site Infection: Prevention and Treatment of Surgical Site Infection. London: RCOG Press; 2008 Oct. (NICE Clinical Guidelines, No. 74.)

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Surgical Site Infection: Prevention and Treatment of Surgical Site Infection.

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Appendix BClinical questions

  1. When, how and what information should be provided for patients for the prevention surgical site infection?
  2. What is the clinical effectiveness of preoperative showering to reduce surgical site infection?
  3. What is the contribution to clinical effectiveness of the timing and number of preoperative washing for the prevention of surgical site infection?
  4. Are preoperative showers with antiseptics cost-effective?
  5. What is the clinical effectiveness of preoperative hair removal from the operative site to reduce surgical site infection?
  6. Does the timing of preoperative hair removal affect the rate of surgical site infection?
  7. What is the cost-effective method of hair removal?
  8. Does patient theatre attire affect the incidence of surgical site infection?
  9. What is the clinical effectiveness of theatre staff wearing non-sterile theatre wear (scrub suits, masks, hats, overshoes) for the prevention of surgical site infection?
  10. Does staff exiting and re-entering the operating room affect the incidence of surgical site infection?
  11. Does patient nasal decontamination to eliminate Staphylococcus aureus affect the rate of surgical site infection?
  12. What is the contribution to clinical effectiveness of the timing of nasal decontamination for the prevention of surgical site infection?
  13. What is the cost-effectiveness of mupirocin nasal ointment for the prevention of surgical site infection caused by Staphylococcus aureus?
  14. Does mechanical bowel preparation reduce the rate of surgical site infection?
  15. Does the removal of hand jewellery, artificial nails and nail polish reduce the incidence of surgical site infection?
  16. What is the clinical effectiveness of parenteral or oral antibiotic prophylaxis for the prevention of surgical site infection compared with placebo or no antibiotic in patients undergoing surgery involving a skin incision?
  17. For which types of surgery would prophylaxis by clinically and cost-effective? When should antibiotic prophylaxis be given – pre/peri/postoperatively?
  18. What is the clinical hand decontamination strategy to use between subsequent surgeries?
  19. What is the cost-effective hand decontamination strategy to use between subsequent surgeries?
  20. Is the use of incise drapes clinically and cost-effective in reducing the incidence of surgical site infection?
  21. Which incise drapes are clinically and cost-effective in reducing the incidence of surgical site infection?
  22. Is the use of gowns clinically effective in reducing the incidence of surgical site infection?
  23. Is the use of reusable or disposable surgical drapes and gowns related to surgical site infection?
  24. Is there a difference between double- versus single-gloving affecting the incidence of surgical site infection?
  25. Does the puncture rate of gloves correlate to the incidence of surgical site infection?
  26. Is the use of preoperative skin antiseptics clinically effective in the prevention of surgical site infection?
  27. Does use of diathermy for surgical incisions affect the rate of surgical site infection?
  28. Is patient perioperative oxygenation clinically effective for the prevention of surgical site infection?
  29. What is the clinical effectiveness of perioperative perfusion and hydration for the prevention of surgical site infection?
  30. What is the clinical effectiveness of strict blood glucose control to reduce surgical site infection?
  31. Is intracavity lavage or wound irrigation clinically effective for the prevention of surgical site infection?
  32. Is the application of intraoperative topical antiseptics/antimicrobials before wound closure clinically effective in reducing surgical site infection rates?
  33. Which type of suture is clinically effective as a closure method?
  34. Which type of suture is clinically and cost-effective as a closure method?
  35. Which type of dressing is advocated for immediate postoperative wound/incision coverage? Is it clinically and cost-effective to use interactive dressings in the immediate postoperative management of a surgical wound to prevent surgical site infection?
  36. Is there any clinical evidence to support the use of a postoperative non-touch dressing change technique rather than the use of a clean dressing change technique in relation to the incidence of surgical site infection?
  37. Is it clinically and cost-effective to use a wound cleansing solution for the management of a surgical wound healing by primary or secondary intention to reduce the incidence of surgical site infection?
  38. Is it cost-effective to use a wound cleansing solution for the management of a surgical wound healing by secondary intention to reduce the incidence of surgical site infection?
  39. What is the clinical effectiveness of topical antimicrobials to reduce surgical site infection?
  40. Is it clinically effective to use topical antiseptics and antibiotics for the management of surgical wounds healing by secondary intention? Which is the most clinically effective dressing in the management of surgical wounds healing by secondary intention?
  41. Is the use of debridement techniques clinically effective in the prevention and management of surgical site infection?
Copyright © 2008, National Collaborating Centre for Women’s and Children’s Health.

No part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK [www.cla.co.uk]. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

Bookshelf ID: NBK53727

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