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Cover of Parkinson’s Disease

Parkinson’s Disease

Pathogenesis and Clinical Aspects

Editors: Thomas B. Stoker, BA, MB BChir, MRCP UK and Julia C. Greenland, MCRP, MRes.

Editor Information
Brisbane (AU): Codon Publications; .
ISBN-13: 978-0-9944381-6-4

Parkinson’s disease is an increasingly common neurodegenerative condition, which causes not only dysfunction of movement but also a broad range of nonmotor features, including mood disturbance, sleep dysfunction, autonomic dysfunction, cognitive deficits, dementia, and neuropsychiatric symptoms. A major conundrum in this condition is understanding its striking clinical variability, which encompasses a spectrum from a benign phenotype with levodopa-responsive symptoms and minimal progression, to a malignant phenotype with rapid progression to severe gait dysfunction, falls and dementia. This book integrates the considerable expertise of a range of authors from different disciplines, from clinicians through to basic scientists, to present a comprehensive and up-to-date overview of Parkinson’s disease. In recent years, we have made significant progress in understanding the pathological and genetic basis of Parkinson’s disease and its heterogeneous forms, and the first section of the book is dedicated to reviewing this. The variable clinical features of Parkinson’s disease and its differential diagnosis are then considered. The final section provides a detailed overview of treatment approaches, including not only pharmacological therapies but also surgical therapies including deep brain stimulation and cell transplantation strategies. The combination of basic biology, clinical knowledge and therapeutics gives this book a very broad appeal. It will be of value to clinicians and health professionals caring for patients with Parkinson’s disease, as well as providing an excellent introduction for junior researchers entering the field.

Contents

Parkinson’s Disease: Pathogenesis and Clinical Aspects

ISBN: 978-0-9944381-6-4

DOI: http://dx.doi.org/10.15586/codonpublications.parkinsonsdisease.2018

Edited by

Thomas B. Stoker, BA, MB BChir, MRCP UK and Julia C. Greenland, MCRP, MRes

John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, UK

Published by

Codon Publications

Brisbane, QLD 4122, Australia

Copyright© 2018 Codon Publications

This open access book is published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). https://creativecommons.org/licenses/by-nc/4.0/

Users are allowed to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material for any non-commercial purpose), as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source.

Notice to the user

The views and opinions expressed in this book are believed to be accurate at the time of publication. The publisher, editors or authors cannot be held responsible or liable for any errors, omissions or consequences arising from the use of the information contained in this book. The publisher makes no warranty, implicit or explicit, with respect to the contents of this book, or its use.

First Published in December 2018

Printed in Australia

A free online version is available at https://codonpublications.com

Copyright © 2018 Codon Publications.

This open access book is published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Users are allowed to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material for any non-commercial purpose), as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source.

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