Polyethylene Glycol

Publication Details

Estimated reading time: 1 minute

CASRN: 25322-68-3

image 127314511 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

Polyethylene glycol is very poorly absorbed from the gastrointestinal tract, so it does not enter breastmilk.[1] No special precautions are required and it may be the laxative of choice during breastfeeding.[2,3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

(Constipation) Bisacodyl, Docusate, Magnesium Hydroxide, Psyllium, Sodium Phosphate; (Irritable Bowel Syndrome) Linaclotide, Lubiprostone, Plecanatide, Psyllium, Tenapanor

References

1.
Clowse ME, Förger F, Hwang C, et al. Minimal to no transfer of certolizumab pegol into breast milk: Results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study. Ann Rheum Dis 2017;76:1890-6 [PMC free article: PMC5705850] [PubMed: 28814432]
2.
Lewis JH, Weingold AB and the Committee of FDA-Related Matters American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol 1985;80:912-23 [PubMed: 2864852]
3.
Gharehbaghi K, Gharehbaghi DR, Wierrani F, et al. Treatment of chronic functional constipation during pregnancy and lactation. Z Geburtshilfe Neonatol 2016;220:9-15 [PubMed: 26866689]

Substance Identification

Substance Name

Polyethylene Glycol

CAS Registry Number

25322-68-3

Drug Class

Breastfeeding

Lactation

Milk, Human

Gastrointestinal Agents

Laxatives

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