NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Cover of Drugs and Lactation Database (LactMed)

Drugs and Lactation Database (LactMed) [Internet].

Show details

Glasdegib

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 1095173-27-5

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

No information is available on glasdegib during breastfeeding. It is 91% bound to plasma proteins, so amounts in milk are likely to be low. With a half-life of 17.4 hours, it is likely to be eliminated from milk by 4 to 7 days after the last dose. However, the manufacturer recommends that breastfeeding be discontinued during glasdegib therapy and for at least 30 days after the last dose.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Substance Identification

Substance Name

Glasdegib

CAS Registry Number

1095173-27-5

Drug Class

  • Breast Feeding
  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Protein Kinase Inhibitors
  • Signal Transduction Inhibitors

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Views

Related information

Similar articles in PubMed

  • Review Crizotinib[Drugs and Lactation Database (...]
    Review Crizotinib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Dacomitinib[Drugs and Lactation Database (...]
    Review Dacomitinib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Binimetinib[Drugs and Lactation Database (...]
    Review Binimetinib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Gilteritinib[Drugs and Lactation Database (...]
    Review Gilteritinib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Alectinib[Drugs and Lactation Database (...]
    Review Alectinib
    . Drugs and Lactation Database (LactMed). 2006
See reviews...See all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...