FIGURE 2-5. Wide variation of patients’ baseline risk (their risk of suffering a bad outcome in the absence of treatment) is one reason trial results don’t apply equally to all patients.

FIGURE 2-5Wide variation of patients’ baseline risk (their risk of suffering a bad outcome in the absence of treatment) is one reason trial results don’t apply equally to all patients

SOURCE: Adapted from Kent, D, and R Hayward, When averages hid individual differences in clinical trials, American Scientist, 2007, vol. 95 (Kent 2007).

From: 2, The Evolving Evidence Base—Methodologic and Policy Challenges

Cover of The Learning Healthcare System
The Learning Healthcare System: Workshop Summary.
Institute of Medicine (US) Roundtable on Evidence-Based Medicine; Olsen LA, Aisner D, McGinnis JM, editors.
Washington (DC): National Academies Press (US); 2007.
Copyright © 2007, National Academy of Sciences.

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