Figure 4.1. Transmission Electron microscopy images of mouse platelets illustrating various stages of activation, associated with microvascular thrombosis induced by photochemical injury.

Figure 4.1

Transmission Electron microscopy images of mouse platelets illustrating various stages of activation, associated with microvascular thrombosis induced by photochemical injury. A) discoid-shape platelet revealing a dense granule with a characteristic “bull’s eye” appearance (black arrow), multiple granules (arrowheads), open canalicular system and tubules (white arrows). B) platelet undergoing shape change and reorganization of granules. C) aggregate of platelets revealing extensive shape change, and paucity of granules within the aggregate. A partially activated platelet revealing dense and other granules is evident within the aggregate. Bar = 500 nm. Electron microscopy performed by Alan Burns, Ph.D. (University of Houston, Houston, TX).

From: Chapter 4, Platelet Aggregation

Cover of Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis
Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis.
Rumbaut RE, Thiagarajan P.
San Rafael (CA): Morgan & Claypool Life Sciences; 2010.
Copyright © 2010 by Morgan & Claypool Life Sciences.

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