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Pes Anserine Bursitis

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Last Update: July 18, 2021.

Continuing Education Activity

The pes anserine describes a region where tendinous structures of the semitendinosus, gracilis, and sartorius muscles join to insert at the medial knee. The pes anserine bursa is sandwiched between the proximal medial tibia and the insertion point of the 3 tendons. Pes anserine bursitis is a clinical entity associated with pain at the medial knee and upper tibial region. This activity describes the evaluation and management of pes anserine bursitis and highlights the interprofessional team's role in improving care for affected patients.


  • Describe the anatomy of the pes anserine and its bursa.
  • Identify underlying risk factors for developing pes anserine bursitis.
  • Outline limb-threatening conditions that may mimic pes anserine bursitis.
  • Explain a well-coordinated, interprofessional team approach to provide effective care to patients affected by pes anserine bursitis.
Access free multiple choice questions on this topic.


Bursitis is the general term used to describe inflammation of any bursae. The bursae are the cavitary structures lined with synovial tissue that cushion and assist during the motion of joints and muscles. Bursitis is usually accompanied by tenderness; however, swelling and redness may also be present.

Pes anserine bursitis is a clinical entity associated with pain at the medial knee and upper tibial region. The term “pes anserine” comes from the Latin referring to “goose’s foot,” which the tendinous structures of the semitendinosus, gracilis, and sartorius muscles are said to resemble as they join to insert at the medial knee. The pes anserine bursa is sandwiched between the proximal medial tibia and the insertion point of the three tendons.[1]

A more generic term, pes anserine pain syndrome, has been applied to refer to medial knee pain, which may or may not include inflammation of the bursa sac. This article focuses on the clinical entity of pes anserine bursitis, unless otherwise specifically stated.


As in other knee conditions, mechanical derangement, direct trauma, obesity, and overuse have all been implicated in the development of pes anserine bursitis. Medial knee osteoarthritis is an early and common finding in patients with this condition. In particular, sports may make one prone to pes anserine inflammatory conditions, including running, basketball, and racquet sports.[2]


The exact frequency of this condition in the general population is unclear as there is extensive overlap with other knee conditions. However, in one large study of over 10,000 persons, pes anserine pain was prevalent in approximately one-third of 1% of these individuals. The association of pes anserine pain (but not necessarily bursitis) with concomitant osteoarthritis was noted in one study to be over 90%.[3]


Multiple reports suggest that pes anserine bursitis is more common in overweight middle-aged females. There is an established association of pes anserine pain with diabetes mellitus. In many patients with established knee osteoarthritis, the inflammation of the pes anserine bursae may not be the primary pathology but rather a sequela of earlier knee complications.[4]

Mechanical derangement at the medial knee joint is surmised to cause localized inflammation to the surrounding tendinous structures. This may include medial meniscus protrusion and displacement of the medial collateral ligament. Subsequently, the anserine bursa may become inflamed as well.

History and Physical

Patients with pes anserine bursitis likely will complain of pain on the inside (medial aspect) of the knee, particularly with rising from a seated position, going upstairs, or sitting with their legs crossed. The semitendinosus, gracilis, and sartorius function in unison in the act of crossing one leg over the other; thus, this motion typically will elicit the pain seen in pes anserine bursitis.

Additionally, there may be subjective complaints of muscle weakness and decreased range of motion of the knee joint. Tenderness is invariably present over at the insertion of the pes anserine tendons, “goose’s foot,” at the medial knee and upper medial tibia.  Swelling may or may not be present. In patients with osteoarthritis, the clinician should have heightened suspicion for the possibility of pes anserine pain.

On physical examination, the affected knee should initially be evaluated in full extension. Tenderness will likely be present in the medial knee joint and may extend along the proximal, medial tibial region. With knee flexion to 90 degrees, tenderness may be palpated along the medial tendinous structures of the pes anserine group as they travel to insert along the medial tibial region. The pes anserine bursa lies directly beneath the tendons at their insertion.


Generally speaking, imaging does not assist with the diagnosis of pes anserine bursitis. However, plain knee radiographs are usually obtained to observe for any underlying bony abnormalities, including osteoarthritis.[5]

Ultrasonography may be used as an adjunct to evaluate other causes of localized swelling, including joint effusions. Though rarely indicated in an urgent setting, magnetic resonance imaging (MRI) may help assess for knee pathology and rule out alternative diagnoses.

Treatment / Management

Basics of initial therapy for pes anserine bursitis include the usual typical recommendations for many musculoskeletal disorders, including rest, ice, and short-term nonsteroidal anti-inflammatory drug use (unless otherwise contraindicated based on the patient’s medical history). Additionally, in the setting of obesity and deconditioning, weight loss and muscle strengthening exercises (particularly the quadriceps muscle group) can help with the long-term resolution of symptoms.[6]

In patients with underlying osteoarthritis, treatment may need to be directed at this entity as well. Steroid injections are reserved for refractory symptoms but may be used initially with severe pain or in patients with nocturnal pain symptoms.

Additional modalities for treatment include therapeutic ultrasound, physical therapy, and transcutaneous electrical nerve stimulation (TENS).[7]

Differential Diagnosis

The differential for a patient presenting with localized pain in the area of the pes anserine bursa is broad. It is paramount the treating clinician rules out of any infectious pathology such as septic bursitis or osteomyelitis. Gouty changes to the bursa are another diagnostic possibility. Neuropathic pain from compression of local structures (e.g., the saphenous nerve) may present similarly with medial knee discomfort. Furthermore, several other bursae may become inflamed (e.g., semimembranosus bursa or tibial collateral ligament bursa) within the knee joint, and the patient may present similarly.[8]

Mass or space-occupying lesions within the knee that may present with medial knee pain include, but are not limited to, lipoma, hemangioma, giant cell tumor, tuberculosis, liposarcoma, and myelolipoma.

In the setting of trauma, medial meniscal tear or rupture must remain in the differential. Tibial stress fractures can occur in the setting of repetitive sports activities. Osteonecrosis can occur in those patients who are on long-term steroid therapy.

Less urgent pathology to include in the differential for pes anserine bursitis includes fat pad tenderness in overweight patients or fibromyalgia. In fibromyalgia patients, the pain is typically more symmetric and bilateral.


The prognosis of most cases of pes anserine bursitis is a long-term resolution after limiting the inciting factors, including avoiding sports or repetitive activities that may worsen the patient’s pain. Duration of symptoms varies based on underlying conditions, including osteoarthritis, obesity, and deconditioning.[9]


Complications of pes anserine bursitis are rare but usually result from a lack of treatment. These can include increased pain and inflammation, with a subsequent weakening of the muscles and tendons around the knee joint.[10][9]

Deterrence and Patient Education

Patient education centers around preventing reinjury and proper steps to return to play for athletes. These include using proper form when training, hamstring stretching along with quadriceps strengthening, proper footwear for activity level and intensity, maintaining healthy body weight, and cautious return to competitive training and activity.

Pearls and Other Issues

Pes anserine bursitis refers specifically to the inflammatory condition of the bursal sac located between the muscular tendons (sartorius, gracilis, and semitendinosus) and their insertion at the proximal medial tibia. These three muscles act to help in the “cross-legged” position. Thus, any repetitive activity that requires this form of motion may exacerbate the symptoms of the condition.

Underlying osteoarthritis, obesity, and the female gender are risk factors for developing this syndrome.

Treatment of pes anserine bursitis is generally supportive with steroid injections reserved for refractory cases.

Enhancing Healthcare Team Outcomes

Patients with pes anserine bursitis may be seen in all practice settings from outpatient offices, urgent care centers, and emergency departments. Referral to a specialist is not often needed unless the patient has another underlying condition that may be causing this syndrome or if there is unrelenting discomfort despite supportive measures.

Most data on diagnosis and treatment of pes anserine is derived from case series, relying heavily on expert opinions for direction and care goals. An interprofessional team approach will result in the best outcomes. [Level 5]

Review Questions


Hubbard MJ, Hildebrand BA, Battafarano MM, Battafarano DF. Common Soft Tissue Musculoskeletal Pain Disorders. Prim Care. 2018 Jun;45(2):289-303. [PubMed: 29759125]
Sapp GH, Herman DC. Pay Attention to the Pes Anserine in Knee Osteoarthritis. Curr Sports Med Rep. 2018 Feb;17(2):41. [PubMed: 29420344]
Alvarez-Nemegyei J, Peláez-Ballestas I, Goñi M, Julián-Santiago F, García-García C, Quintana R, Silvestre AM, García-Olivera I, Mathern NA, Loyola-Sanchez A, Conti S, Sanabria AJ, Pons-Estel BA. Prevalence of rheumatic regional pain syndromes in Latin-American indigenous groups: a census study based on COPCORD methodology and syndrome-specific diagnostic criteria. Clin Rheumatol. 2016 Jul;35 Suppl 1:63-70. [PMC free article: PMC4954835] [PubMed: 26833395]
Pompan DC. Pes Anserine Bursitis: An Underdiagnosed Cause of Knee Pain in Overweight Women. Am Fam Physician. 2016 Feb 01;93(3):170. [PubMed: 26926606]
Rennie WJ, Saifuddin A. Pes anserine bursitis: incidence in symptomatic knees and clinical presentation. Skeletal Radiol. 2005 Jul;34(7):395-8. [PubMed: 15940489]
Sarifakioglu B, Afsar SI, Yalbuzdag SA, Ustaömer K, Bayramoğlu M. Comparison of the efficacy of physical therapy and corticosteroid injection in the treatment of pes anserine tendino-bursitis. J Phys Ther Sci. 2016 Jul;28(7):1993-7. [PMC free article: PMC4968491] [PubMed: 27512249]
Yoon HS, Kim SE, Suh YR, Seo YI, Kim HA. Correlation between ultrasonographic findings and the response to corticosteroid injection in pes anserinus tendinobursitis syndrome in knee osteoarthritis patients. J Korean Med Sci. 2005 Feb;20(1):109-12. [PMC free article: PMC2808555] [PubMed: 15716614]
Zhao H, Maheshwari AV, Kumar D, Malawer MM. Giant cell tumor of the pes anserine bursa (extra-articular pigmented villonodular bursitis): a case report and review of the literature. Case Rep Med. 2011;2011:491470. [PMC free article: PMC3114461] [PubMed: 21687595]
Yagi S, Sata M. Rupture of pes anserine bursa in a patient with pes anserine pain syndrome due to osteoarthritis. J Med Invest. 2019;66(1.2):211-212. [PubMed: 31064945]
Creighton A, Stecco A, Whitelaw A, Probst D, Hunt D. Fascial Manipulation method as a treatment for pain, atrophy and skin depigmentation after pes anserine bursa corticosteroid injection: A case report. J Bodyw Mov Ther. 2020 Oct;24(4):280-285. [PubMed: 33218523]
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Bookshelf ID: NBK532941PMID: 30422536


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