FIGURE 4.2. Relationship between oxygen uptake and blood flow (oxygen delivery).

FIGURE 4.2

Relationship between oxygen uptake and blood flow (oxygen delivery). The curves depicted represent a composite of those shown in Figure 3.4. Alterations in tissue oxidative metabolism shift the curve vertically, while alterations in perfused capillary density shift the curve horizontally. The dot represents blood flow under control conditions, and the lettered arrows represent the potential effects of vasoactive agents on oxygen uptake. Pathway A is taken by a vasodilator that increases oxidative metabolism; Pathway B is taken by a vasodilator that does not affect oxidative metabolism or perfused capillary density; Pathway C is taken by a vasodilator that decreases capillary density; Pathway D is taken by a vasodilator that decreases metabolism; Pathway E is taken by a vasoconstrictor that decreases metabolism; Pathway F is taken by a vasoconstrictor that decreases capillary density; Pathway G is taken by a vasoconstrictor that does not affect metabolism or capillary density; Pathway H is taken by a vasoconstrictor that increases capillary density; Pathway I is taken by a vasoconstrictor that increases metabolism. Used with permission from Am. J. Physiol. 1982; 243: pp. G1–G9.

From: Chapter 4, Extrinsic Vasoregulation: Neural and Humoral

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The Gastrointestinal Circulation.
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