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Hartling L, Bond K, Harvey K, et al. Developing and Testing a Tool for the Classification of Study Designs in Systematic Reviews of Interventions and Exposures [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2010 Dec.

Cover of Developing and Testing a Tool for the Classification of Study Designs in Systematic Reviews of Interventions and Exposures

Developing and Testing a Tool for the Classification of Study Designs in Systematic Reviews of Interventions and Exposures [Internet].

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Appendix FChanges Made Between Round One and Round Two Algorithm

Round OneRound Two
Was there a comparison between interventions/exposures/observations (including before and after measurements on the same individuals)?Was there a comparison to assess the effect/association of an intervention/exposure and an outcome? This could be between ≥ 2 groups or within the same individual or group(s) comparing pre- and post-intervention measures.
Were disease and exposure information assessed concurrently (e.g., by survey)?Was information on the intervention/exposure gathered by the investigators concurrently (e.g., by survey)?
Was the study experimental (i.e., investigators had direct control over study conditions including decisions around allocation and timing of interventions)?Was the study experimental (i.e., investigators had direct control over study conditions including: allocation to ≥ 2 interventions, timing of interventions, choice of outcome(s), and timing of outcome assessments?
Was more than one group compared?Did all the participants receive the same intervention/exposure?
Was there a single cohort?Did investigators identify the participants from a single source (e.g., same setting or time period)?
Were at least three measurements made before and after intervention/exposure?Were there ≥ 3 measurements before and ≥ 3 measurements after the intervention/exposure?
Were at least three measurements made before and after intervention/exposure?Were threre ≥ 3 measurements before and ≥ 3 measurements after the intervention/exposure?

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