NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Cover of Drugs and Lactation Database (LactMed)

Drugs and Lactation Database (LactMed) [Internet].

Show details

Flunarizine

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 52468-60-7

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

Flunarizine is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. No information is available on the use of flunarizine during breastfeeding. Because of its long half-life of 19 days in children, expert opinion recommends that flunarizine not be used in migraine prophylaxis.[1][2][3] An alternate drug is preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Pringsheim T, Davenport WJ, Mackie G et al. Canadian Headache Society guideline for migraine prophylaxis. Can J Neurol Sci. 2012;39 (Suppl 2):S1-2. [PubMed: 22683887]
2.
Negro A, Delaruelle Z, Ivanova TA et al. Headache and pregnancy: A systematic review. J Headache Pain. 2017;18:106. [PMC free article: PMC5648730] [PubMed: 29052046]
3.
Davanzo R, Bua J, Paloni G et al. Breastfeeding and migraine drugs. Eur J Clin Pharmacol. 2014;70:1313-24. [PubMed: 25217187]

Substance Identification

Substance Name

Flunarizine

CAS Registry Number

52468-60-7

Drug Class

  • Breast Feeding
  • Calcium Channel Blockers
  • Histamine H1 Antagonists
  • Vasodilator Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Views

Related information

Similar articles in PubMed

  • Review Cinnarizine[Drugs and Lactation Database (...]
    Review Cinnarizine
    . Drugs and Lactation Database (LactMed). 2006
  • Review Flunitrazepam[Drugs and Lactation Database (...]
    Review Flunitrazepam
    . Drugs and Lactation Database (LactMed). 2006
  • Review Prazosin[Drugs and Lactation Database (...]
    Review Prazosin
    . Drugs and Lactation Database (LactMed). 2006
  • Review Mianserin[Drugs and Lactation Database (...]
    Review Mianserin
    . Drugs and Lactation Database (LactMed). 2006
  • Review Ethyl Loflazepate[Drugs and Lactation Database (...]
    Review Ethyl Loflazepate
    . Drugs and Lactation Database (LactMed). 2006
See reviews...See all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...