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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Cinnarizine

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 298-57-7

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

Cinnarizine is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. No information is available on the use of cinnarizine during breastfeeding. Expert opinion recommends that cinnarizine not be used in migraine prophylaxis.[1][2][3] An alternate drug is preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Pringsheim T, Davenport WJ, Mackie G et al. Canadian Headache Society guideline for migraine prophylaxis. Can J Neurol Sci. 2012;39 (Suppl 2):S1-2. [PubMed: 22683887]
2.
Negro A, Delaruelle Z, Ivanova TA et al. Headache and pregnancy: A systematic review. J Headache Pain. 2017;18:106. [PMC free article: PMC5648730] [PubMed: 29052046]
3.
Davanzo R, Bua J, Paloni G et al. Breastfeeding and migraine drugs. Eur J Clin Pharmacol. 2014;70:1313-24. [PubMed: 25217187]

Substance Identification

Substance Name

Cinnarizine

CAS Registry Number

298-57-7

Drug Class

  • Breast Feeding
  • Calcium Channel Blockers
  • Histamine H1 Antagonists
  • Vasodilator Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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