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Kahwati LC, Weber RP, Pan H, et al. Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: An Evidence Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 Apr. (Evidence Synthesis, No. 160.)
Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: An Evidence Review for the U.S. Preventive Services Task Force [Internet].
Show detailsAppendix A Table 1Serum Vitamin D Level Reference Ranges
| Serum Level (nmol/L) | Equivalent Range in ng/ml | NAM Description* | Qualitative Term Used to Describe This Range† |
|---|---|---|---|
| <30 nmol/L | <12 ng/ml | Persons with levels in this range are at risk of deficiency relative to bone health outcomes | Severe deficiency |
| Between 30-50 nmol/L | Between 12-20 ng/ml | Some, but not all, persons in this range are at risk of deficiency relative to bone health outcomes | Deficiency |
| Between 50-75 nmol/L | Betw een 20-30 ng/dl | Most, but not all, persons with levels in this range are sufficient relative to bone health outcomes | Some refer to this range as insufficiency; others contend this range is sufficiency. |
| >75 nmol/L | >30 ng/ml | Persons with levels in this range do not consistently have an increased benefit relative to bone health outcomes | Sufficiency |
| Above 125 nmol/L | Above 50 ng/ml | Levels in this range may be cause for concern | – |
- *
As described in: Dietary Reference Intakes for Calcium and Vitamin D. IOM (Institute of Medicine). 2011 Washington, DC: The National Academies Press.5
- †
These are not terms attributed by NAM; rather, these are descriptors commonly found in the literature describing these ranges. Experts disagree about the terms that should be used to describe these ranges, whether these ranges adequately reflect the evidence, and whether these ranges reflect clinical thresholds for action related to supplementation.
Abbreviations: NAM=National Academy of Medicine (formerly Institute of Medicine); ng/ml=nanogram per milliliter; nmol/L=nanomole per liter.
- Appendix A Table 1, Serum Vitamin D Level Reference Ranges - Vitamin D, Calcium,...Appendix A Table 1, Serum Vitamin D Level Reference Ranges - Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: An Evidence Review for the U.S. Preventive Services Task Force
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