Analysis of the entire coding region: Mutation scanning

Synonyms: scanning, mutation screening, mutation scanning

A 2-step process by which the entire coding region of a gene is first analyzed via one of a variety of methods (such as CSGE, DGGE, SSCP, DHPLC or TGCE) to identify sequence alterations. These methods do not identify the specific nucleotide change(s) and must be followed by further analysis (usually sequencing) to identify the specific sequence alteration

Related Terms: Analysis of the entire coding region: Sequence analysis; CSGE; DGGE; DNA-based testing; molecular genetic testing; PCR; SSCP; Targeted mutation analysis

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