10.8.1What is the prevalence of rubella susceptibility in pregnant women in the UK?

StudyRef.PopulationInterventionOutcomesResultsCommentsStudy typeEL
Miller et al., 1997423Antenatal population in England and WalesImpact of 1994 mumps and rubella vaccination campaign on future incidence of rubella in pregnant womenAntenatal susceptibility
Incidence and risk of rubella infection in susceptible pregnant women
Susceptibility in antenatal population: 2% in nulliparous women (735/36509) and 1.2% (839/67615) in parous women for 1994/5 (p < 0.0001)
Susceptibility in Asian (n = 5000) vs. non- Asian (n = 62,346) population was 4.4% compared with 1.3%
In 1995, incidence in nulliparous 2/431 (risk/1000 = 4.6), in parous 0/547; overall risk 2/1005
Data on rubella monitored through serologically confirmed cases, terminated pregnancies because of rubella and notifications to NCRSP.SV3
Tookey et al., 2002424145,284 pregnant women from former North West Thames region from 1996–1999 from which antenatal rubella screening data were available for 137,398Retrospective analysis of routinely collected dataRubella susceptibility2.5% overall
Breakdown by ethnicity: 1.7% white were susceptible vs. 3.7% of women from Mediterranean region, 5.1% of Asian, 4.8% black and 8% Oriental
Database used for this analysis includes about 90% of the deliveries in the areaSV3

From: Evidence tables

Cover of Antenatal Care
Antenatal Care: Routine Care for the Healthy Pregnant Woman.
NICE Clinical Guidelines, No. 62.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2008 Mar.
Copyright © 2008, National Collaborating Centre for Women’s and Children’s Health.

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