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Cover of Sequence-Based Classification of Select Agents

Sequence-Based Classification of Select Agents

A Brighter Line


Washington (DC): National Academies Press (US); .
ISBN-13: 978-0-309-15904-3ISBN-10: 0-309-15904-0


In 2006, the National Science Advisory Board for Biodefense (NSABB) issued Addressing Biosecurity Concerns Related to the Synthesis of Select Agents, which called for expert evaluation to determine whether an alternative framework based on predicted features and properties encoded by nucleic acids, such as virulence or pathogenicity, can be developed and used in lieu of the current finite list of specific agents and taxonomic definitions. Our committee was tasked with identifying “the scientific advances that would be necessary to permit serious consideration of developing and implementing an oversight system for Select Agents that is based on predicted features and properties encoded by nucleic acids rather than a relatively static list of specific agents and taxonomic definitions.”


This study was supported by Contract No. NO1-OD-4-2139 (Task Order #216) between the National Academy of Sciences and the National Institutes of Health.

The content of this publication does not necessarily reflect the views or policies of the National Institutes of Health, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. government.

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

Copyright © 2010, National Academy of Sciences.
Bookshelf ID: NBK50873PMID: 21210555DOI: 10.17226/12970


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