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Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level.
The exact role and regulation of magnesium in particular remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system actvity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism.
There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration.
This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesium’s involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behaviour.
It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesium’s role in biological systems that has inspired the collation of this volume of work.
ISBN (electronic) 978‐0‐9870730‐5‐1
ISBN (paperback) 978‐0‐9870730‐6‐8
Published by
University of Adelaide Press
Barr Smith Library
THe University of Adelaide
South Australia
5005
press@adelaide.edu.au
www.adelaide.edu.au/press
Copyright© 2011 The Authors
This book is copyright. Apart from any fair dealing for the purposes of private study, research, criticism or review as permitted under the Copyright Act, no part may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise without the prior written permission. Address all inquiries to the Director at the above address.
Book design: Robert Vink
Cover design: Emma Spoehr. Photograph with permission, istockphoto.com
Paperback printed by Griffin Press, South Australia
This book is copyright. Apart from any fair dealing for the purposes of private study, research, criticism or review as permitted under the Copyright Act, no part may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise without the prior written permission. Address all inquiries to the Director at the above address.
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