Table 3Selected Compounds Based on Confirmatory Screening

PubChem CIDPubChem SIDSelectivity Index (SI) TC50/IC50CPE IC50 (μM) (AID-1621)Cytotox TC50 (μM) (AID-1650)Titer reduction assay (AID-2024)
3713338872190611.42>2535.5inactive
133407496454979.2210.85>100inactive
92827749646879>5.0719.72>100active
248295722402842>8.4511.84>100active
264226822405569>3.7526.67>100inactive
248679722402901>4.8520.62>100inactive
2474694549643126>3.99425.04>100active
322363549643860>5.72417.47>100inactive
1618736224780348>5.3818.59>100inactive

From: A Cell Based Assay for the Identification of Lead Compounds with Anti-Viral Activity Against West Nile Virus

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.