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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Gadobutrol

Last Revision: February 28, 2019.

Estimated reading time: 1 minute

CASRN: 770691-21-9

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

There is no published experience with gadobutrol during breastfeeding. Guidelines developed by several professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3][4] Gadobutrol is one of the most stable gadolinium agents, theoretically making it one of the safer drugs to use during breastfeeding. However, because there is no published experience with gadobutrol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Gadobutrol, Gadopentetate, Gadoteridol, Gadoterate

References

1.
American College of Radiology Committee on Drugs and Contrast Media. Administration of contrast media to breast-feeding mothers. In, ACR manual on contrast media. 2017;Version 10.3:102-3. https://www​.acr.org/~​/media/37D84428BF1D4E1B9A3A2918DA9E27A3.pdf.
2.
Patenaude Y, Pugash D, Lim K et al. The use of magnetic resonance imaging in the obstetric patient. J Obstet Gynaecol Can. 2014;36:349-55. [PubMed: 24798674]
3.
Committee Opinion No. 723: Guidelines for Diagnostic Imaging During Pregnancy and Lactation. Obstet Gynecol. 2017;130:e210-e216. [PubMed: 28937575]
4.
European Society of Urogenital Radiology. ESUR guidelines on contrast media. 2018;Version 10.0. http://www​.esur-cm.org/index.php/en/

Substance Identification

Substance Name

Gadobutrol

CAS Registry Number

770691-21-9

Drug Class

  • Breast Feeding
  • Contrast Media
  • Diagnostic Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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