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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.
Drug Levels and Effects
Summary of Use during Lactation
Uva ursi (Arctostaphylos uva-ursi) leaves contain arbutin, which is hydrolyzed to hydroquinone. Uva ursi has no specific lactation-related uses, but is most often used as a urinary antiseptic. No data exist on the excretion of any components of uva ursi into breastmilk or on the safety and efficacy of uva ursi in nursing mothers or infants. Uva ursi is generally considered to be contraindicated during breastfeeding because of a lack of data and its potential toxicity.[1][2]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
(Urinary Antiseptic) Methenamine Hippurate, Methenamine Mandelate, Nitrofurantoin
References
- 1.
- Kopec K. Herbal medications and breastfeeding. J Hum Lact. 1999;15:157-61. [PubMed: 10578793]
- 2.
- Nice F, Coghlan RJ, Birmingham BT. Which herbals are safe to take while breastfeeding? Here's a guide to popular herbs and their potential risk to nurslings. US Pharm. 2000;25:1-9.
Substance Identification
Substance Name
Uva Ursi
Scientific Name
Arctostaphylos uva-ursi
Drug Class
- Breast Feeding
- Complementary Therapies
- Phytotherapy
- Plants, Medicinal
- Anti-Infective Agents, Urinary
Administrative Information
LactMed Record Number
982
Last Revision Date
20181203
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- PubMedLinks to PubMed
- Review Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations.[Int J Toxicol. 2013]Review Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations.de Arriba SG, Naser B, Nolte KU. Int J Toxicol. 2013 Nov-Dec; 32(6):442-53.
- UHPLC-PDA-ESI-TOF/MS metabolic profiling of Arctostaphylos pungens and Arctostaphylos uva-ursi. A comparative study of phenolic compounds from leaf methanolic extracts.[Phytochemistry. 2015]UHPLC-PDA-ESI-TOF/MS metabolic profiling of Arctostaphylos pungens and Arctostaphylos uva-ursi. A comparative study of phenolic compounds from leaf methanolic extracts.Panusa A, Petrucci R, Marrosu G, Multari G, Gallo FR. Phytochemistry. 2015 Jul; 115:79-88. Epub 2015 Feb 18.
- In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein.[Can J Physiol Pharmacol. 2007]In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein.Chauhan B, Yu C, Krantis A, Scott I, Arnason JT, Marles RJ, Foster BC. Can J Physiol Pharmacol. 2007 Nov; 85(11):1099-107.
- Mycorrhiza of the host-specific Lactarius deterrimus on the roots of Picea abies and Arctostaphylos uva-ursi.[Mycorrhiza. 2006]Mycorrhiza of the host-specific Lactarius deterrimus on the roots of Picea abies and Arctostaphylos uva-ursi.Mühlmann O, Göbl F. Mycorrhiza. 2006 Jun; 16(4):245-250. Epub 2006 Feb 22.
- Review Botanical medicines for the urinary tract.[World J Urol. 2002]Review Botanical medicines for the urinary tract.Yarnell E. World J Urol. 2002 Nov; 20(5):285-93. Epub 2002 Oct 17.
- Uva Ursi - Drugs and Lactation Database (LactMed)Uva Ursi - Drugs and Lactation Database (LactMed)
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