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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Dibucaine

Last Revision: November 16, 2020.

Estimated reading time: 1 minute

CASRN: 85-79-0

image 134970600 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

Topical dibucaine has not been studied during breastfeeding, but is unlikely to affect her breastfed infant if it is applied away from the breast. However, dibucaine ointment should not be applied to the nipple area, because ingestion by infants has caused seizures, arrhythmias, cardiovascular collapse and death after direct ingestion by toddlers.[1,2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Lidocaine

References

1.
Dayan PS, Litovitz TL, Crouch BI, et al. Fatal accidental dibucaine poisoning in children. Ann Emerg Med. 1996;28:442–5. [PubMed: 8839533]
2.
Nelsen J, Holland M, Dougherty M, et al. Severe central nervous system and cardiovascular toxicity in a pediatric patient after ingestion of an over-the-counter local anesthetic. Pediatr Emerg Care. 2009;25:670–3. [PubMed: 19834416]

Substance Identification

Substance Name

Dibucaine

CAS Registry Number

85-79-0

Drug Class

Breast Feeding

Lactation

Anesthetics, Local

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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