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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Flurazepam

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 17617-23-1

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the excretion of flurazepam into breastmilk. One case of infant sedation was reported in a woman taking flurazepam along with other sedating drugs during breastfeeding. Because of the long duration of action of flurazepam, an alternate hypnotic is preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. One mother who was taking flurazepam (dose unclear), clonazepam 0.25 mg twice daily, 1 mg of bupropion daily, and 0.75 mg of risperidone daily reported sedation in her breastfed infant.[1]

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Zaleplon, Zolpidem

References

1.
Kelly LE, Poon S, Madadi P, Koren G. Neonatal benzodiazepines exposure during breastfeeding. J Pediatr. 2012;161:448-51. [PubMed: 22504099]

Substance Identification

Substance Name

Flurazepam

CAS Registry Number

17617-23-1

Drug Class

  • Breast Feeding
  • Benzodiazepines
  • Hypnotics and Sedatives

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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