Summary of Use during Lactation

Because no information is available on the use of iloperidone during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Iloperidone causes minimal increases in serum prolactin.[1,2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternate Drugs to Consider

Haloperidol, Olanzapine, Risperidone

References

1.

Cutler AJ. Iloperidone: A new option for the treatment of schizophrenia. Expert Rev Neurother. 2009;9:1727–41. [PubMed: 19951132]

2.

Weiden PJ, Cutler AJ, Polymeropoulos MH, et al. Safety profile of iloperidone: A pooled analysis of 6-week acute-phase pivotal trials. J Clin Psychopharmacol. 2008;28(2) Suppl 1:S12–9. [PubMed: 18334908]

Substance Name

Iloperidone

CAS Registry Number

133454-47-4

Drug Class

Breast Feeding

Lactation

Antipsychotic Agents