Summary of Use during Lactation

There is no published experience with gadoxetate during breastfeeding. Guidelines developed by several North American professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3] However, because there is no published experience with gadoxetate during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Gadobenate, Gadobutrol, Gadopentetate, Gadoteridol, Gadoterate

References

1.

American College of Radiology Committee on Drugs and Contrast Media. Administration of contrast media to breast-feeding mothers. In, ACR manual on contrast media. 2017;Version 10.3:102-3. https://www​.acr.org/~​/media/37D84428BF1D4E1B9A3A2918DA9E27A3.pdf.

2.

Patenaude Y, Pugash D, Lim K et al. The use of magnetic resonance imaging in the obstetric patient. J Obstet Gynaecol Can. 2014;36:349-55. 24798674 . [PubMed: 24798674]

3.

Committee Opinion No. 723: Guidelines for Diagnostic Imaging During Pregnancy and Lactation. Obstet Gynecol. 2017;130:e210-e216. [PubMed: 28937575]

Substance Name

Gadoxetate

CAS Registry Number

135326-11-3

Drug Class

• Breast Feeding
• Lactation
• Contrast Media
• Diagnostic Agents