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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Zolmitriptan

Last Revision: February 17, 2020.

Estimated reading time: 1 minute

CASRN: 139264-17-8

image 135017989 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

Preliminary evidence indicates that zolmitriptan levels in breastmilk are low. Amounts ingested by the infant are small and unlikely to affect the nursing infant, especially if the infant is older than 2 months.

Drug Levels

Maternal Levels. Four women who were at least 1 month postpartum using zolmitriptan to treat migraine provided milk samples at intervals over a 24-hour period after a single dose. The authors estimated the weight-adjusted infant dosage to be 2.1% (range 0.7 to 5.3%).[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Eletriptan, Rizatriptan, Sumatriptan

References

1.
Amundsen S, Nordeng H, Fuskevåg OM, et al. Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding. Reprod Toxicol. 2019;88:141. [CrossRef]

Substance Identification

Substance Name

Zolmitriptan

CAS Registry Number

139264-17-8

Drug Class

Breast Feeding

Lactation

Serotonin Agonists

Vasoconstrictor Agents

Serotonin 5-HT1 Receptor Agonists

Triptans

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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