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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 396-01-0
Drug Levels and Effects
Summary of Use during Lactation
Because there is no published experience with triamterene during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Intense diuresis can suppress lactation;[1-4] however, it is unlikely that triamterene alone is sufficiently potent to cause this effect.
Alternate Drugs to Consider
References
- 1.
- Healy M. Suppressing lactation with oral diuretics. Lancet 1961;1:1353-4. doi:10.1016/S0140-6736(61)90289-6 [PubMed: 4134342] [CrossRef]
- 2.
- Reiher KH. Suppression of lactation by stimulation of diuresis. Zentralbl Gynakol 1963;85:188-90. [PubMed: 13973786]
- 3.
- Stout G. Suppression of lactation. Br Med J 1962;1:1150. [PubMed: 18117911]
- 4.
- Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. [PubMed: 3858]
Substance Identification
Substance Name
Triamterene
CAS Registry Number
396-01-0
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- A new antihypertensive agent: Maxzide (75 mg triamterene/50 mg hydrochlorothiazide).[Am J Med. 1984]A new antihypertensive agent: Maxzide (75 mg triamterene/50 mg hydrochlorothiazide).Blume CD, Williams RL. Am J Med. 1984 Nov 5; 77(5A):52-8.
- A comparison of the anti-hypertensive effectiveness of two triameterene/hydrochlorothiazide combinations: Maxzide versus Dyazide.[J Clin Pharmacol. 1990]A comparison of the anti-hypertensive effectiveness of two triameterene/hydrochlorothiazide combinations: Maxzide versus Dyazide.Casner PR, Dillon KR. J Clin Pharmacol. 1990 Aug; 30(8):715-9.
- [CLINICAL REPORT ON THE TREATMENT OF CARDIAC DECOMPENSATION WITH 2,4,7-TRIAMINO-6-PHENYLPTERIDINE (JATROPUR, TRIAMTERENE)].[Wien Klin Wochenschr. 1963][CLINICAL REPORT ON THE TREATMENT OF CARDIAC DECOMPENSATION WITH 2,4,7-TRIAMINO-6-PHENYLPTERIDINE (JATROPUR, TRIAMTERENE)].ESCH I, KRAMMER J. Wien Klin Wochenschr. 1963 Sep 6; 75:634-7.
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