NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Cover of Drugs and Lactation Database (LactMed)

Drugs and Lactation Database (LactMed) [Internet].

Show details

Torsemide

Last Revision: January 20, 2020.

Estimated reading time: 1 minute

CASRN: 56211-40-6

image 135003852 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

Because little information is available on the use of torsemide during breastfeeding and because intense diuresis might decrease lactation, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Low doses of torsemide may not suppress lactation.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Intense diuresis, fluid restriction and breast binding have been used to suppress lactation immediately postpartum.[1-3] The added contribution of the diuretic to the other measures, which are effective in suppressing lactation, has not been studied.

Women who delivered following pre-eclampsia were randomized to receive either torsemide 20 mg daily or placebo for 5 days starting within 24 hours after delivery. Eighty percent of the women who received torsemide and 75% of women who received placebo breastfed. One mother who received torsemide and none who received placebo reported a decrease in breastmilk.[4]

Alternate Drugs to Consider

Chlorothiazide, Hydrochlorothiazide

References

1.
Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353–4.
2.
Stout G. Suppression of lactation. Br Med J 1962;1:1150. Letter. PMC1958377.
3.
Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J. 1976;50:251–2. [PubMed: 3858]
4.
Viteri OA, Alrais MA, Pedroza C, et al. Torsemide for prevention of persistent postpartum hypertension in women with preeclampsia: A randomized controlled trial. Obstet Gynecol. 2018;132:1185–91. [PubMed: 30303905]

Substance Identification

Substance Name

Torsemide

CAS Registry Number

56211-40-6

Drug Class

Breast Feeding

Lactation

Antihypertensive Agents

Loop Diuretics

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Views

Related information

Similar articles in PubMed

  • Review Acetohexamide[Drugs and Lactation Database (...]
    Review Acetohexamide
    . Drugs and Lactation Database (LactMed). 2006
  • Review Ethacrynic Acid[Drugs and Lactation Database (...]
    Review Ethacrynic Acid
    . Drugs and Lactation Database (LactMed). 2006
  • Review Glimepiride[Drugs and Lactation Database (...]
    Review Glimepiride
    . Drugs and Lactation Database (LactMed). 2006
  • Review Fenofibrate[Drugs and Lactation Database (...]
    Review Fenofibrate
    . Drugs and Lactation Database (LactMed). 2006
  • Review Meclofenamate[Drugs and Lactation Database (...]
    Review Meclofenamate
    . Drugs and Lactation Database (LactMed). 2006
See reviews...See all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...