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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.
CASRN: 38304-91-5

Drug Levels and Effects
Summary of Use during Lactation
Because of the minimal amount of information on this potent agent, use minoxidil with caution, particularly when therapy involves a large maternal dosage or breastfeeding a newborn. Topical minoxidil should pose low risk to the breastfed infant.
Drug Levels
Maternal Levels. In one case report, a 2-month-postpartum mother who was taking minoxidil 5 mg twice daily was given a, oral dose of 7.5 mg. The peak milk level of minoxidil plus glucuronide conjugate was 45.1 mcg/L at 1 hour after the dose. Milk levels paralleled serum levels, falling rapidly after the first hour to a concentration of 12.4 mcg/L at 3 hours, 4 mcg/L at 6 hours, 1.9 mcg/L at 9 hours, 0.8 mcg/L at 12 hours after the dose.[1]
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
No hypertrichosis or other abnormal signs were seen in one infant breastfed for 2 months of maternal minoxidil therapy.[1]
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
- 1.
- Valdivieso A, Valdes G, Spiro TE et al. Minoxidil in breast milk. Ann Intern Med. 1985;102:135. Letter. [PubMed: 3966734]
Substance Identification
Substance Name
Minoxidil
CAS Registry Number
38304-91-5
Drug Class
- Breast Feeding
- Antihypertensive Agents
- Vasodilator Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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