NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Cover of Drugs and Lactation Database (LactMed)

Drugs and Lactation Database (LactMed) [Internet].

Show details

Empagliflozin

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 461432-26-8

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the clinical use of empagliflozin during breastfeeding. Empagliflozin is an uncharged molecule that is 86% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend empagliflozin during breastfeeding because of a theoretical risk to the infant's developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Acarbose, Glipizide, Glyburide, Insulin, Metformin, Miglitol

Substance Identification

Substance Name

Empagliflozin

CAS Registry Number

461432-26-8

Drug Class

  • Breast Feeding
  • Hypoglycemic Agents
  • Sodium-Glucose Cotransporter 2 Inhibitors
  • SGLT2 Inhibitors

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site .

Views

Related information

Similar articles in PubMed

  • Review Dapagliflozin[Drugs and Lactation Database (...]
    Review Dapagliflozin
    . Drugs and Lactation Database (LactMed). 2006
  • Review Ertugliflozin[Drugs and Lactation Database (...]
    Review Ertugliflozin
    . Drugs and Lactation Database (LactMed). 2006
  • Review Canagliflozin[Drugs and Lactation Database (...]
    Review Canagliflozin
    . Drugs and Lactation Database (LactMed). 2006
  • Review Lovastatin[Drugs and Lactation Database (...]
    Review Lovastatin
    . Drugs and Lactation Database (LactMed). 2006
  • Review Simvastatin[Drugs and Lactation Database (...]
    Review Simvastatin
    . Drugs and Lactation Database (LactMed). 2006
See reviews...See all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...