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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.
CASRN: 16506-27-7
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of bendamustine during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as bendamustine.[1] The manufacturer recommends that breastfeeding be discontinued during bendamustine therapy. Based on the half-life of the drug and its metabolites, the drug should be eliminated from the milk by 24-48 hours after the last dose.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Some evidence indicates that carmustine can increase serum prolactin.[2]
Substance Identification
Substance Name
Bendamustine
CAS Registry Number
16506-27-7
Drug Class
- Breast Feeding
- Antineoplastic Agents, Alkylating
- Nitrosourea Compounds
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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