NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Cover of Drugs and Lactation Database (LactMed)

Drugs and Lactation Database (LactMed) [Internet].

Show details

Bendamustine

Last Revision: December 3, 2018.

CASRN: 16506-27-7

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the use of bendamustine during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as bendamustine.[1] The manufacturer recommends that breastfeeding be discontinued during bendamustine therapy. Based on the half-life of the drug and its metabolites, the drug should be eliminated from the milk by 24-48 hours after the last dose.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Some evidence indicates that carmustine can increase serum prolactin.[2]

Substance Identification

Substance Name

Bendamustine

CAS Registry Number

16506-27-7

Drug Class

  • Breast Feeding
  • Antineoplastic Agents, Alkylating
  • Nitrosourea Compounds

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Views

Related information

Similar articles in PubMed

  • Review Carmustine[Drugs and Lactation Database (...]
    Review Carmustine
    . Drugs and Lactation Database (LactMed). 2006
  • Review Cyclophosphamide[Drugs and Lactation Database (...]
    Review Cyclophosphamide
    . Drugs and Lactation Database (LactMed). 2006
  • Review Exemestane[Drugs and Lactation Database (...]
    Review Exemestane
    . Drugs and Lactation Database (LactMed). 2006
  • Review Dactinomycin[Drugs and Lactation Database (...]
    Review Dactinomycin
    . Drugs and Lactation Database (LactMed). 2006
  • Review Azacitidine[Drugs and Lactation Database (...]
    Review Azacitidine
    . Drugs and Lactation Database (LactMed). 2006
See reviews...See all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...