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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Amiloride

Last Revision: December 3, 2018.

CASRN: 2609-46-3

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the use of amiloride during breastfeeding, so an alternate drug may be preferred.

Drug Levels

Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Intense diuresis can suppress lactation;[1][2] however, it is unlikely that amiloride alone is sufficiently potent to cause this effect.

Alternate Drugs to Consider

Spironolactone

References

1.
Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353-4.
2.
Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J. 1976;50:251-2. [PubMed: 3858]

Substance Identification

Substance Name

Amiloride

CAS Registry Number

2609-46-3

Drug Class

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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