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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.
CASRN: 851199-59-2
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of linaclotide during breastfeeding. Linaclotide is minimally absorbed from the gastrointestinal tract and the drug and its active metabolite is not measurable in plasma following administration of recommended doses. Linaclotide would not be expected to enter the breastmilk and cause any adverse effects in breastfed infants
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
(Irritable Bowel Syndrome) Lubiprostone, Plecanatide, Polyethylene Glycol, Psyllium, Tenapanor
Substance Identification
Substance Name
Linaclotide
CAS Registry Number
851199-59-2
Drug Class
Breast Feeding
Gastrointestinal Agents
Peptides
Guanylate Cyclase C Agonists
Laxatives
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Linaclotide - Drugs and Lactation Database (LactMed)Linaclotide - Drugs and Lactation Database (LactMed)
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