NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Cover of Drugs and Lactation Database (LactMed)

Drugs and Lactation Database (LactMed) [Internet].

Show details

Sonidegib

Last Revision: December 3, 2018.

CASRN: 956697-53-3

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the clinical use of sonidegib during breastfeeding. Because sonidegib is 97% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 28 days and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during sonidegib therapy.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Substance Identification

Substance Name

Sonidegib

CAS Registry Number

956697-53-3

Drug Class

  • Breast Feeding
  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Hedgehog Pathway Inhibitors
  • Signal Transduction Inhibitors

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Views

Related information

Similar articles in PubMed

  • Review Enasidenib[Drugs and Lactation Database (...]
    Review Enasidenib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Nilotinib[Drugs and Lactation Database (...]
    Review Nilotinib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Axitinib[Drugs and Lactation Database (...]
    Review Axitinib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Vismodegib[Drugs and Lactation Database (...]
    Review Vismodegib
    . Drugs and Lactation Database (LactMed). 2006
  • Review Ponatinib[Drugs and Lactation Database (...]
    Review Ponatinib
    . Drugs and Lactation Database (LactMed). 2006
See reviews...See all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...