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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.
Drug Levels and Effects
Summary of Use during Lactation
Evidence from a few mothers who received deep brain stimulation indicated that no difficulty was encountered with lactation, other than minor discomfort with chest neurostimulators.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
In a case series of pregnant patients treated for dystonia with deep brain stimulation (DBS), 4 of 5 mothers breastfed their 6 infants (1 set of twins and 2 siblings) with no apparent difficulty. One mother chose not to breastfeed, unrelated to DBS. Two mothers reported minor discomfort during breastfeeding with chest neurostimulators.[1]
References
- 1.
- Ziman N, Coleman RR, Starr PA et al. Pregnancy in a series of dystonia patients treated with deep brain stimulation: Outcomes and management recommendations. Stereotact Funct Neurosurg. 2016;94:60-5. [PubMed: 26977859]
Substance Identification
Substance Name
Deep Brain Stimulation
Drug Class
- Breast Feeding
- Electric Stimulation Therapy
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- Radiofrequency neurotomy for a patient with deep brain stimulators: proposed safety guidelines.[Pain Med. 2009]Radiofrequency neurotomy for a patient with deep brain stimulators: proposed safety guidelines.Osborne MD. Pain Med. 2009 Sep; 10(6):1046-9. Epub 2009 Sep 9.
- Rechargeable Internal Pulse Generators as Initial Neurostimulators for Deep Brain Stimulation in Patients With Movement Disorders.[Neuromodulation. 2018]Rechargeable Internal Pulse Generators as Initial Neurostimulators for Deep Brain Stimulation in Patients With Movement Disorders.Jakobs M, Kloß M, Unterberg A, Kiening K. Neuromodulation. 2018 Aug; 21(6):604-610. Epub 2018 Jan 8.
- Open-loop deep brain stimulation for the treatment of epilepsy: a systematic review of clinical outcomes over the past decade (2008-present).[Neurosurg Focus. 2018]Open-loop deep brain stimulation for the treatment of epilepsy: a systematic review of clinical outcomes over the past decade (2008-present).Zhou JJ, Chen T, Farber SH, Shetter AG, Ponce FA. Neurosurg Focus. 2018 Aug; 45(2):E5.
- Review Pacemakers, Deep Brain Stimulators, Cochlear Implants, and Nerve Stimulators: A Review of Common Devices Encountered in the Dermatologic Surgery Patient.[Dermatol Surg. 2019]Review Pacemakers, Deep Brain Stimulators, Cochlear Implants, and Nerve Stimulators: A Review of Common Devices Encountered in the Dermatologic Surgery Patient.Tripathi SV, Hurst EA. Dermatol Surg. 2019 Oct; 45(10):1228-1236.
- Review Deep brain stimulation in obsessive-compulsive disorder.[Prog Brain Res. 2009]Review Deep brain stimulation in obsessive-compulsive disorder.Denys D, Mantione M. Prog Brain Res. 2009; 175:419-27.
- Deep Brain Stimulation - Drugs and Lactation Database (LactMed)Deep Brain Stimulation - Drugs and Lactation Database (LactMed)
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