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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Edoxaban

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 480449-70-5

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

Because no information is available on the use of edoxaban during breastfeeding and the drug is orally absorbable, an alternate drug is preferred while nursing a newborn or preterm infant.[1][2][3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Acenocoumarol, Dalteparin, Enoxaparin, Heparin, Warfarin

References

1.
Bates SM, Greer IA, Middeldorp S et al. VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141 (2 Suppl):e691S-736S. [PMC free article: PMC3278054] [PubMed: 22315276]
2.
Vanassche T, Vandenbriele C, Peerlinck K, Verhamme P. Pharmacotherapy with oral Xa inhibitors for venous thromboembolism. Expert Opin Pharmacother. 2015;16:645-58. [PubMed: 25554350]
3.
Cohen H, Arachchillage DR, Beyer-Westendorf J et al. Direct oral anticoagulants and women. Semin Thromb Hemost. 2016;42:789-97. [PubMed: 27706531]

Substance Identification

Substance Name

Edoxaban

CAS Registry Number

480449-70-5

Drug Class

  • Breast Feeding
  • Anticoagulants
  • Antithrombins

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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