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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Vilanterol

Last Revision: December 3, 2018.

Estimated reading time: 1 minute

CASRN: 503068-34-6

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

Although no published data exist on the use of vilanterol during lactation, data from the related drug, terbutaline, indicate that very little is expected to be excreted into breastmilk.[1] Vilanterol is available only in combination products such as Breo Ellipta and Anoro Ellipta. The authors of several reviews agree that use of inhaled bronchodilators is acceptable during breastfeeding because of the low bioavailability and maternal serum levels after use.[2][3][4][5] Combination products such as Breo Ellipta and Anoro Ellipta are likely to be acceptable for similar reasons.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Formoterol, Salmeterol

References

1.
Lindberg C, Boreus LO, de Chateau P et al. Transfer of terbutaline into breast milk. Eur J Resp Dis Suppl. 1984;134:87-91. [PubMed: 6586490]
2.
McDonald CF, Burdon JG. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust. 1996;165:485-8. [PubMed: 8937369]
3.
Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994;10:39-41. [PubMed: 7619245]
4.
Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001;56:325-8. [PMC free article: PMC1746013] [PubMed: 11254828]
5.
Taddio A, Ito S. Drugs and breast-feeding. In, Koren G, ed. Maternal-fetal toxicology. A clinician's guide. 3rd ed. New York. Marcel Dekker. 2001;177-32.

Substance Identification

Substance Name

Vilanterol

CAS Registry Number

503068-34-6

Drug Class

  • Breast Feeding
  • Beta Adrenergic Agonists
  • Bronchodilator Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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