NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

Cover of Drugs and Lactation Database (LactMed)

Drugs and Lactation Database (LactMed) [Internet].

Show details

Pulsatilla

Last Revision: February 15, 2021.

Estimated reading time: 1 minute

Drug Levels and Effects

Summary of Use during Lactation

Pulsatilla (Anemone pulsatilla and other related species) contains ranunculin, protoanemonin, and anemonin as well as triterpene saponins and flavonoids. The fresh plant is extremely irritating to the skin, gastrointestinal tract and mucous membranes. Allergic reactions have been reported to pulsatilla. Homeopathic preparations of pulsatilla are reportedly used for sore nipples and mastitis,[1] to reduce an overabundant milk supply,[2] or to increase milk supply.[3] Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[4,5] No scientifically valid clinical trials support either of these uses. Because of a lack of information, other agents may be preferred in nursing mothers.

Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information about dietary supplements is available elsewhere on the LactMed Web site.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Castro M. Homeopathy. A theoretical framework and clinical application. J Nurse Midwifery. 1999;44:280–90. [PubMed: 10380446]
2.
Eglash A. Treatment of maternal hypergalactia. Breastfeed Med. 2014;9:423–5. [PMC free article: PMC4216483] [PubMed: 25361472]
3.
Winterfeld U, Meyer Y, Panchaud A, et al. Management of deficient lactation in Switzerland and Canada: A survey of midwives' current practices. Breastfeed Med. 2012;7:317–8. [PubMed: 22224508]
4.
Brodribb W. ABM Clinical Protocol #9. Use of galactogogues in initiating or augmenting maternal milk production, second revision 2018. Breastfeed Med. 2018;13:307–14. [PubMed: 29902083]
5.
Breastfeeding challenges: ACOG Committee Opinion, Number 820. Obstet Gynecol. 2021;137:e42–e53. [PubMed: 33481531]

Substance Identification

Substance Name

Pulsatilla

Scientific Name

Anemone pulsatilla

Drug Class

Breast Feeding

Lactation

Complementary Therapies

Phytotherapy

Plants, Medicinal

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Views

Related information

  • PMC
    PubMed Central citations
  • PubMed
    Links to PubMed

Similar articles in PubMed

  • Review Astragalus[Drugs and Lactation Database (...]
    Review Astragalus
    . Drugs and Lactation Database (LactMed). 2006
  • Review Chamomile[Drugs and Lactation Database (...]
    Review Chamomile
    . Drugs and Lactation Database (LactMed). 2006
  • Review Stinging Nettle[Drugs and Lactation Database (...]
    Review Stinging Nettle
    . Drugs and Lactation Database (LactMed). 2006
  • Review Dandelion[Drugs and Lactation Database (...]
    Review Dandelion
    . Drugs and Lactation Database (LactMed). 2006
  • Review Withania[Drugs and Lactation Database (...]
    Review Withania
    . Drugs and Lactation Database (LactMed). 2006
See reviews...See all...

Recent Activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...