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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.

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Drugs and Lactation Database (LactMed) [Internet].

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Water O 15

Last Revision: June 21, 2021.

Estimated reading time: 1 minute

CASRN: 24286-21-3

Drug Levels and Effects

Summary of Use during Lactation

Information in this record refers to the use of water O 15 as a diagnostic agent. No information is available on the use of water O 15 during breastfeeding. United States and international authorities state that breastfeeding need not be interrupted after administration of radiopharmaceuticals containing oxygen-15.[1,2]

Drug Levels

Oxygen 15 decays by positron emission with a half-life of 122 seconds

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.


Mattsson S, Johansson L, Leide Svegborn S, et al. Radiation dose to patients from radiopharmaceuticals: A compendium of current information related to frequently used substances. Annex D. Recommendations on breast-feeding interruptions. Ann ICRP. 2015;44(2) Suppl:319–21. [PubMed: 26069086]
Dilsizian V, Metter D, Palestro C, et al. Advisory Committee on Medical Uses of Isotopes (ACMUI) Sub-Committee on Nursing Mother Guidelines for the Medical Administration of Radioactive Material. Final Report Submitted: January 31, 2019. https://www​.nrc.gov/docs​/ML1903/ML19038A498.pdf.

Substance Identification

Substance Name

Water O 15

CAS Registry Number


Drug Class

Breast Feeding



Oxygen Radioisotopes

Diagnostic Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.


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