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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 16974-53-1
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of pancuronium during breastfeeding. Because it is highly polar and poorly absorbed orally, it is not likely to reach the breastmilk in high concentration or to reach the bloodstream of the infant.[1,2] When a combination of anesthetic agents is used for a procedure, follow the recommendations for the most problematic medication used during the procedure.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
- 1.
- Spigset O. Anaesthetic agents and excretion in breast milk. Acta Anaesthesiol Scand. 1994;38:94–103. [PubMed: 8171959]
- 2.
- Dalal PG, Bosak J, Berlin C. Safety of the breast-feeding infant after maternal anesthesia. Paediatr Anaesth. 2014;24:359–71. [PubMed: 24372776]
Substance Identification
Substance Name
Pancuronium
CAS Registry Number
15500-66-0; 16974-53-1
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Review Vecuronium.[Drugs and Lactation Database (...]Review Vecuronium.. Drugs and Lactation Database (LactMed®). 2006
- Review Rocuronium.[Drugs and Lactation Database (...]Review Rocuronium.. Drugs and Lactation Database (LactMed®). 2006
- Configurational analysis and relative binding affinities of 16-methyl-5alpha-androstane derivatives.[Steroids. 2001]Configurational analysis and relative binding affinities of 16-methyl-5alpha-androstane derivatives.Tapolcsányi P, Wölfling J, Tóth I, Szécsi M, Forgó P, Schneider G. Steroids. 2001 Nov; 66(11):833-43.
- Vecuronium bromide and its advanced intermediates: A crystallographic and spectroscopic study.[Steroids. 2021]Vecuronium bromide and its advanced intermediates: A crystallographic and spectroscopic study.Ciceri S, Colombo D, Ferraboschi P, Grisenti P, Iannone M, Mori M, Meneghetti F. Steroids. 2021 Dec; 176:108928. Epub 2021 Oct 13.
- On the pharmacology of Org 6338 (2beta, 16beta-dipiperidino - 5alpha - androstan - 3alpha - ol acetate dimethobromide), a new steroidal neuromuscular blocking agent.[J Pharm Pharmacol. 1975]On the pharmacology of Org 6338 (2beta, 16beta-dipiperidino - 5alpha - androstan - 3alpha - ol acetate dimethobromide), a new steroidal neuromuscular blocking agent.Sugrue MF, Duff N, McIndewar I. J Pharm Pharmacol. 1975 Oct; 27(10):721-7.
- Pancuronium - Drugs and Lactation Database (LactMed®)Pancuronium - Drugs and Lactation Database (LactMed®)
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