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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-.
CASRN: 706808-37-9
Drug Levels and Effects
Summary of Use during Lactation
Inforamtion from one patient indicates that the drug may be used in nursing mothers; however, more data are needed. The manufacturer recommends avoiding nursing if belatacept is given. Because the drug's half-life is 8 to 10 days, it may be more than a month after a dose before the drug is absent from breastmilk.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
A mother with a liver transplant was maintained on belatacept 10 mg/kg monthly, slow-release tacrolimus (Envarsus and Veloxis) 2 mg daily, azathioprine 25 mg daily, and prednisone 2.5 mg daily. She breastfed her infant for a year (extent not stated). The infant’s growth and cognitive milestones were normal.[1]
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
- 1.
- Klintmalm GB, Gunby RT Jr. Successful pregnancy in a liver transplant recipient on belatacept. Liver Transpl. 2020;26:1193–4. [PubMed: 32337853]
Substance Identification
Substance Name
Belatacept
CAS Registry Number
706808-37-9
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