≥2 ARMS/GROUPS: DICHOTOMOUS OUTCOMES (e.g. OR, RR, %death)

UI Author Year Outcome Exposure Categories(e.g., Tertiles)/Intervention Groups Mean Vit D level/dose ***** Mean Ca level/dose No. of Cases (Event) * No. of Non- cases ** Crude or Adjusted analysis? Outcome Metric (e.g. OR, RR, HR, %) Outcome effect size CI/SE/SD ** P between groups *** P for trend ****
11045788 Platz 2000 Distal colorectal adenoma 1,25(OH)2D quartile 1 22.3 pg/ml 97 80 Adjusted OR 1.00 (ref) 0.4
quartile 2 29.0 pg/ml 71 84 0.64 0.41–1.02
quartile 3 33.9 pg/ml 84 80 0.80 0.50–1.30
quartile 4 40.9 pg/ml 74 82 0.71 0.43–1.15
11045788 Platz 2000 Distal colorectal adenoma 25(OH)D quartile 1 16.3 pg/ml 103 82 Adjusted OR 1.00 (ref) 1.0
quartile 2 22.6 pg/ml 62 80 0.64 0.41–1.00
quartile 3 28.3 pg/ml 61 82 0.58 0.36–0.95
quartile 4 38.0 pg/ml 100 82 1.04 0.66–1.66
11045788 Platz 2000 Rectal adenoma 1,25(OH)2D quartile 1 22.3 pg/ml 16 17 Adjusted OR 1.00 (ref) 0.9
quartile 2 29.0 pg/ml 18 14 1.35 0.41–4.43
quartile 3 33.9 pg/ml 13 16 0.58 0.16–2.09
quartile 4 40.9 pg/ml 18 18 1.06 0.30–3.73
11045788 Platz 2000 Rectal adenoma 25(OH)D quartile 1 16.3 pg/ml 24 18 Adjusted OR 1.00 (ref) 0.9
quartile 2 22.6 pg/ml 7 16 0.38 0.12–0.19
quartile 3 28.3 pg/ml 10 13 0.34 0.08–1.42
quartile 4 38.0 pg/ml 24 18 1.59 0.50–5.03
11045788 Platz 2000 Distal colon adenoma 1,25(OH)2D quartile 1 22.3 pg/ml 81 63 Adjusted OR 1.00 (ref) 0.2
quartile 2 29.0 pg/ml 53 70 0.51 0.30–0.86
quartile 3 33.9 pg/ml 71 64 0.78 0.45–1.34
quartile 4 40.9 pg/ml 56 64 0.60 0.34–1.04
11045788 Platz 2000 Distal colon adenoma 25(OH)D quartile 1 16.3 pg/ml 79 64 Adjusted OR 1.00 (ref) 1.0
quartile 2 22.6 pg/ml 55 64 0.71 0.43–1.18
quartile 3 28.3 pg/ml 51 69 0.60 0.35–1.02
quartile 4 38.0 pg/ml 76 64 1.02 0.60–1.73
11045788 Platz 2000 Distal colorectal adenoma 25(OH)D nd nd nd Adjusted (after 2 years from blood draw only) OR 1.00 (ref) nd Nd “comparable to main analysis”
0.73 nd
0.85 nd
0.96 nd
11045788 Platz 2000 Distal colorectal adenoma 1,25(OH)D quartile 1 nd nd nd Adjusted (season of blood draw taken into account) OR 1.00 (ref) nd Nd “comparable to main analysis”
quartile 2 0.64 nd
quartile 3 0.75 nd
quartile 4 0.68 nd
11045788 Platz 2000 “high-risk” distal colon cancer 25(OH)D quartile 1 16.3 45 36 Adjusted OR 1.00 (ref) 0.9
quartile 2 22.6 24 37 0.54 0.25–1.16
quartile 3 28.3 26 35 0.67 0.31–1.44
quartile 4 38.0 47 34 1.30 0.59–2.86

Duplicate one row per exposure category or intervention group.

*

Number of subjects with outcome

**

Please choose one and delete the others

***

Specify the comparison. For example group 1 vs. 3 = −6; group 1 vs. 2 = −8

****

P value for testing the linear trend of the OR/RR across different categories or doses

*****

median

From: Appendix C, Evidence Tables: L-Q

Cover of Vitamin D and Calcium
Vitamin D and Calcium: A Systematic Review of Health Outcomes.
Evidence Reports/Technology Assessments, No. 183.
Chung M, Balk EM, Brendel M, et al.

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