Regional analgesia – establishing regional analgesia in labour (intrathecal opioids versus epidural local anaesthetics)

Bibliographic reference Study type Evidence level Number of women Women’s characteristics Intervention Comparison Length of follow-up Outcome measures Effect size Source of funding Additional comments
Bucklin BA;Chestnut DH;Hawkins JL; 2002 Jan212Systemati c review - meta- analysisEvidence level: 1+7 trialswomen in labour requiring analgesiaIntervention: intrathecal opioidsComparison: epidural local anaestheticsFollow-up period: intrapartumOutcome Measures: analgesia, mode of birth, adverse eventsspontaneous vaginal birth
RR 1.10 [0.34 to 1.85]

pruritis
RR 14.10 [13.39 to 14.80]

Nausea
RR 0.94 [0.01 to 1.88]
not stated

From: Evidence tables

Cover of Intrapartum Care
Intrapartum Care: Care of Healthy Women and Their Babies During Childbirth.
NICE Clinical Guidelines, No. 55.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2007 Sep.
Copyright © 2007, National Collaborating Centre for Women’s and Children’s Health.

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