Fig. 28.8. Splicing patterns and translation products in the K12 region of the KSHV genome.

Fig. 28.8

Splicing patterns and translation products in the K12 region of the KSHV genome. Transcripts in the K12 region appear to originate upstream of K12. In the case of a primary PEL tumor, a promoter has been identified in the latent region of the genome, within ORF73. Translation appears to occur in different reading frames and from conventional (ATG) as well as unconventional (CTG) start codons.

From: Chapter 28, KSHV gene expression and regulation

Cover of Human Herpesviruses
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.
Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.
Cambridge: Cambridge University Press; 2007.
Copyright © Cambridge University Press 2007.

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