Fig. 24.1. Plasmid maintenance model for EBV and KSHV.

Fig. 24.1

Plasmid maintenance model for EBV and KSHV. EBNA 1 and LANA tether viral genomes to cellular chromosomes. This tethering can occur through numerous chromosome- associated proteins and appears to be sufficient for stable plasmid maintenance.

From: Chapter 24, Maintenance and replication during latency

Cover of Human Herpesviruses
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.
Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.
Cambridge: Cambridge University Press; 2007.
Copyright © Cambridge University Press 2007.

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