Table 54.2Current strength of evidencea for various routes of KSHV transmission in endemic vs. non-endemic areas

Route of transmission Endemic areas Non-endemic areas
Sexual transmission among homosexual men + + + + +
Sexual transmission among heterosexual men and women + + +
Non-sexual horizontal transmission in childhood + + + n.s.
Injection drug use n.s. + + +
Vertical transmission + n.s.
Blood transfusion + + + +
Solid organ transplantation + + + + + +
a

+ denotes weak evidence; + + denotes moderate evidence; + + + denotes definitive or strong evidence; − denotes presence of studies but no supportive evidence; n.s. denotes not yet studied.

From: Chapter 54, The epidemiology of KSHV and its association with malignant disease

Cover of Human Herpesviruses
Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.
Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.
Cambridge: Cambridge University Press; 2007.
Copyright © Cambridge University Press 2007.

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