Appendix D. Excluded studies

Publication Details

The following full-text publications were considered for inclusion but failed to meet the criteria for this report.

Part I. Excluded for Update 4

Part II. Previously excluded

  1. Agrawal RL. Double-blind comparison of Inderal LA (160 mg), Half-Inderal LA (80 mg), and Half-Inderal LA plus bendrofluazide (2. Br. J. Clin. Pract. 1987;41(9):916–920.
  2. Agrawal RL, Alliott RJ, George M, et al. The treatment of hypertension with propranolol and bendrofluazide. Journal of the Royal College of General Practitioners. 1979;29(207):602–606.
  3. Ahmed A, Dell'Italia LJ. Use of beta-blockers in older adults with chronic heart failure. Am. J. Med. Sci. 2004;328(2):100–111.
  4. Ajayi AA, Sofowora GG, Adigun AQ, Asiyanbola B. Adjunctive sympathoplegic therapy to ACE inhibition in Blacks with congestive heart failure: a comparison of alpha-1 with beta-1 blockade on exercise tolerance and cardiac sympathovagal reflex activity. Ethnicity & Disease. 2003;13(1):71–79.
  5. Akbar A, Pearce MY. Spironolactone and propranolol in the management of hypertension. Br. J. Clin. Pract. 1984;38(3):110–114.
  6. Albers GW, Simon LT, Hamik A, Peroutka SJ. Nifedipine versus propranolol for the initial prophylaxis of migraine. Headache. 1989;29(4):215–218.
  7. Alexandrino PT, Alves MM, Pinto Correia J. Propranolol or endoscopic sclerotherapy in the prevention of recurrence of variceal bleeding. J. Hepatol. 1988;7(2):175–185.
  8. Allen RD, Gettes LS, Phalan C, Avington MD. Painless ST-segment depression in patients with angina pectoris. Correlation with daily activities and cigarette smoking. Chest. 1976;69(4):467–473.
  9. Amsterdam EA, Gorlin R, Wolfson S. Evaluation of long-term use of propranolol in angina pectoris. JAMA. 1969;210(1):103–106.
  10. Andren L, Hansson L, Eggertsen R, Hedner T, Karlberg BE. Circulatory effects of noise. Acta Medica Scandinavica. 1983;213(1):31–35.
  11. Angelico M, Carli L, Piat C, et al. Isosorbide-5-mononitrate versus propranolol in the prevention of first bleeding in cirrhosis. Gastroenterology. 1993;104(5):1460–1465.
  12. Anonymous. Unstable angina pectoris: National Cooperative Study Group to Compare Medical and Surgical Therapy. IV. Am. J. Cardiol. 1981;48(3):517–524.
  13. Anonymous. Oxprenolol vs propranolol: a randomized, double-blind, multiclinic trial in hypertensive patients taking hydrochlorothiazide. Veterans Administration Cooperative Study Group. Hypertension. 1981;3(2):250–256.
  14. Anonymous. Metoprolol in acute myocardial infarction. Arrhythmias. Other clinical findings and tolerability. Am. J. Cardiol. 1985;56(14):35G-38G.
  15. Anonymous. Comparison of invasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) phase II trial. The TIMI Study Group. N. Engl. J. Med. 1989;320(10):618–627.
  16. Anonymous. The total ischemic burden European trial (TIBET): design, methodology, and management. The TIBET Study Group. Cardiovascular Drugs & Therapy. 1992;6(4):379–386.
  17. Anonymous. Comparison of the effects of amiodarone versus metoprolol on the frequency of ventricular arrythmias and on mortality after acute myocardial infarction. Am. J. Cardiol. 1993;72:1234–1238.
  18. Anonymous. Effect of carvedilol on mortality and morbidity in patients with chronic heart failure. Circulation. 1996;94(4):592.
  19. Anonymous. New beta blocker reduces heart failure mortality by two-thirds. Geriatrics. 1996;51(1):16–19.
  20. Anonymous. LIFE study--still-blinded results show promise. Cardiovascular Journal of Southern Africa. 2001;12(2):123–124.
  21. Anonymous. A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N. Engl. J. Med. 2001;344(22):1659–1667.
  22. Anonymous. Carvedilol offers women with heart problems the same clinical benefits as men. Cardiovascular Journal of Southern Africa. 2002;13(2):84.
  23. Anonymous. ARB superior to beta blocker in preventing adverse outcomes in older, high-risk hypertensive patients. Geriatrics. 2002;57(5):63–64.
  24. Anonymous. Coreg. Nursing. 2002;32(2):18.
  25. Applegate WB, Phillips HL, Schnaper H, et al. A randomized controlled trial of the effects of three antihypertensive agents on blood pressure control and quality of life in older women. Arch. Intern. Med. 1991;151(9):1817–1823.
  26. Applegate WB, Pressel S, Wittes J, et al. Impact of the treatment of isolated systolic hypertension on behavioral variables. Results from the systolic hypertension in the elderly program. Arch. Intern. Med. 1994;154(19):2154–2160.
  27. Aranda JM, Krause-Steinrauf HJ, Greenberg BH, et al. Comparison of the beta blocker bucindolol in younger versus older patients with heart failure. Am. J. Cardiol. 2002;89(11):1322–1326.
  28. Ardissino D, Savonitto S, Egstrup K, et al. Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. Am. J. Cardiol. 1991;67(11):946–952.
  29. Ardissino D, Savonitto S, Egstrup K, et al. Selection of medical treatment in stable angina pectoris: Results of the International Multicenter Angina Exercise (IMAGE) study. Journal of the American College of Cardiology. 1995;25(7):1516–1521.
  30. Aronow WS. Effect of beta blockers on mortality and morbidity in persons treated for congestive heart failure. J. Am. Geriatr. Soc. 2001;49(3):331–333.
  31. Aronow WS, Ahn C. Effect of beta blockers on incidence of new coronary events in older persons with prior myocardial infarction and diabetes mellitus. Am. J. Cardiol. 2001;87(6):780–781, A788.
  32. Aronow WS, Ahn C, Kronzon I. Effect of propranolol versus no propranolol on total mortality plus nonfatal myocardial infarction in older patients with prior myocardial infarction, congestive heart failure, and left ventricular ejection fraction > or = 40% treated with diuretics plus angiotensin-converting enzyme inhibitors. Am. J. Cardiol. 1997;80(2):207–209.
  33. Aronow WS, Ahn C, Mercando AD, Epstein S, Kronzon I. Decrease in mortality by propranolol in patients with heart disease and complex ventricular arrhythmias is more an anti-ischemic than an antiarrhythmic effect. Am. J. Cardiol. 1994;74(6):613–615.
  34. Arumanayagam M, Chan S, Tong S, Sanderson JE. Antioxidant properties of carvedilol and metoprolol in heart failure: a double-blind randomized controlled trial. J. Cardiovasc. Pharmacol. 2001;37(1):48–54.
  35. Auer J, Weber T, Berent R, et al. A comparison between oral antiarrhythmic drugs in the prevention of atrial fibrillation after cardiac surgery: The Pilot Study of Prevention of Postoperative Atrial Fibrillation (SPPAF), a randomized, placebo-controlled trial. Am. Heart J. 2004;147(4):636–643.
  36. Bai XP, Guo XJ, Zhang LX. Celiprolol vs atenolol in treating hypertension. Chinese Journal of New Drugs and Clinical Remedies. 2001;20(1):43–45.
  37. Bairey CN, Krantz DS, DeQuattro V, Berman DS, Rozanski A. Effect of beta-blockade on low heart rate-related ischemia during mental stress. J. Am. Coll. Cardiol. 1991;17(6):1388–1395.
  38. Balcetyte-Harris N, Tamis JE, Homel P, Menchavez E, Steinberg JS. Randomized study of early intravenous esmolol versus oral beta-blockers in preventing post-CABG atrial fibrillation in high risk patients identified by signal-averaged ECG: Results of a pilot study. Annals of Noninvasive Electrocardiology. 2002;7(2):86–91.
  39. Banares R, Moitinho A, Matilla G, et al. Carvedilol (carv) vs propranolol (prop) in the long-term treatment of portal hypertension (PH) (abstract). J. Hepatol. 2000;32(2).
  40. Barber JM, Murphy FM, Merrett JD. Clinical trial of propranolol in acute myocardial infarction. Ulster Med. J. 1967;36:127–130.
  41. Baxter AJ, Spensley A, Hildreth A, Karimova G, O'Connell JE, Gray CS. Beta blockers in older persons with heart failure: tolerability and impact on quality of life. Heart (British Cardiac Society). 2002;88(6):611–614.
  42. Behan PO, Reid M. Propranolol in the treatment of migraine. Practitioner. 1980;224(1340):201–203.
  43. Beilin LJ, Juel-Jensen BE. Alpha and beta adrenergic blockade in hypertension. Lancet. 1972;1(7758):979–982.
  44. Bekes M, Matos L, Rausch J, Torok E. Treatment of migraine with propranolol. Lancet. 1968;2(7575):980.
  45. Benetos A, Consoli S, Safavian A, Dubanchet A, Safar M. Efficacy, safety, and effects on quality of life of bisoprolol/hydrochlorothiazide versus amlodipine in elderly patients with systolic hypertension. Am. Heart J. 2000;140(4):E11.
  46. Bloem TJJ, Lindner P. Metoprolol in angina pectoris complicated by essential hypertension. A clinical comparison of the antianginal efficacy of metoprolol slow- release tablets (durules(Reg.trademark)) given once daily and propranolol tablets given twice daily. Annals of Clinical Research. 1981;13(Suppl. 30):61–67.
  47. Blumenthal JA, Ekelund LG, Emery CF. Quality of life among hypertensive patients with a diuretic background who are taking atenolol and enalapril. Clinical Pharmacology & Therapeutics. 1990;48(4):447–454.
  48. Boberg J, Larsen FF, Pehrsson SK. The effects of beta blockade with (epanolol) and without (atenolol) intrinsic sympathomimetic activity in stable angina pectoris. The Visacor Study Group. Clin. Cardiol. 1992;15(8):591–595.
  49. Bochkareva EV, Kokurina EV, Metelitsa VI, Pankina VA. Comparative efficacy of proxodolol and propranolol chosen on an individual basis for single and regular use in patients with angina pectoris. Experimental and Clinical Pharmacology. 1994;57(3):51–54.
  50. Boden WE, Bough EW, Reichman MJ, et al. Beneficial effects of high-dose diltiazem in patients with persistent effort angina on beta-blockers and nitrates: a randomized, double-blind, placebo-controlled cross-over study. Circulation. 1985;71(6):1197–1205.
  51. Bohler S, Saubadu S, Scheldewaert R, Figulla HR. Betaxolol versus carvedilol in chronic heart failure (BETACAR study). Arzneimittelforschung. 1999;49(4):311–317.
  52. Boissel JP, Collet JP, Lion L, et al. A randomized comparison of the effect of four antihypertensive monotherapies on the subjective quality of life in previously untreated asymptomatic patients: field trial in general practice. The OCAPI Study Group. J. Hypertens. 1995;13(9):1059–1067.
  53. Bongers V, Sabin GV. Comparison of the effect of two metoprolol formulations on total ischaemic burden. Clinical Drug Investigation. 1999;17(2):103–110.
  54. Boquist S, Ruotolo G, Hellenius ML, Danell-Toverud K, Karpe F, Hamsten A. Effects of a cardioselective beta-blocker on postprandial triglyceride-rich lipoproteins, low density lipoprotein particle size and glucose-insulin homeostasis in middle-aged men with modestly increased cardiovascular risk. Atherosclerosis. 1998;137(2):391–400.
  55. Bordini CA, Arruda MA, Ciciarelli MC, Speciali JG. Propranolol vs flunarizine vs flunarizine plus propranolol in migraine without aura prophylaxis. Arq. Neuropsiquiatr. 1997;55(3B):536–541.
  56. Borer JS, Comerford MB, Sowton E. Assessment of metoprolol, a cardioselective beta-blocking agent, during chronic therapy in patients with angina pectoris. J. Int. Med. Res. 1976;4(1):15–22.
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  58. Brady AR, Gibbs JSR, Greenhalgh RM, Powell JT, Sydes MR, investigators Pt. Perioperative beta-blockade (POBBLE) for patients undergoing infrarenal vascular surgery: results of a randomized double-blind controlled trial. J. Vasc. Surg. Apr 2005;41(4):602–609.
  59. Broekman CP, Haensel SM, Van de Ven LL, Slob AK. Bisoprolol and hypertension: effects on sexual functioning in men. Journal of Sex & Marital Therapy. 1992;18(4):325–331.
  60. Browning RC, Ebbutt A, Russell JG, Mayhew SR. A multicentre study of cardioselective metoprolol (Lopresor) and non-selective propranolol in the management of mild to moderate hypertension. Br. J. Clin. Pract. 1981;35(11–12):399–402.
  61. Brunner HR, Waeber B, Ferguson RK, Turini GA, Gavras H. The position of beta-blockers in antihypertensive therapy. Comparison with other antihypertensive agents. Cardiology. 1979;64(1):88–95.
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  63. Bulpitt CJ, Connor M, Schulte M, Fletcher AE. Bisoprolol and nifedipine retard in elderly hypertensive patients: effect on quality of life. J. Hum. Hypertens. 2000;14(3):205–212.
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  65. Burroughs AK, Panagou E. Pharmacological therapy for portal hypertension: Rationale and results. Semin. Gastrointest. Dis. 1995;6(3):148–164.
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  71. Carruthers G, Dessain P, Fodor G, Newman C, Palmer W, Sim D. Comparative trial of doxazosin and atenolol on cardiovascular risk reduction in systemic hypertension. Am. J. Cardiol. 1993;71(7):575–581.
  72. Castenfors J, Danielsson M. Metoprolol and hydrochlorothiazide in a fixed combination once daily in the treatment of hypertension. Current Therapeutic Research, Clinical & Experimental. 1979;25(2).
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  126. Dorow P, Bethge H, Tonnesmann U. Effects of single oral doses of bisoprolol and atenolol on airway function in nonasthmatic chronic obstructive lung disease and angina pectoris. Eur. J. Clin. Pharmacol. 1986;31(2):143–147.
  127. Dotremont G, De Geest H. The use of propranolol (inderal) in acute myocardial infarction. Acta Clin. Belg. 1968;23(3):163–176.
  128. Egstrup K. Randomized double-blind comparison of metoprolol, nifedipine, and their combination in chronic stable angina: effects on total ischemic activity and heart rate at onset of ischemia. Am. Heart J. 1988;116(4):971–978.
  129. Egstrup K, Andersen PE, Jr. Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol. Am. J. Cardiol. 1993;71(2):177–183.
  130. Egstrup K, Gundersen T, Harkonen R, Karlsson E, Lundgren B. The antianginal efficacy and tolerability of controlled-release metoprolol once daily: a comparison with conventional metoprolol tablets twice daily. Eur. J. Clin. Pharmacol. 1988;33(Suppl):S45–49.
  131. El Sahly AM, Shendy MS, Abdel Rahman HM. Medical treatment of portal hypertension using verapamil, ketanserin and propranolol alone and in combinations [abstract]. Gut. 1996;39(Suppl 3).
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