Table 69Therapeutic effects of gonadal steroids on development of AD

TreatmentHR (95% CI) for probable dementia
CEE1.76 (1.19 to 2.60); P = 0.005
Exclusion participants with low baseline 3MS1.77 (0.74 to 4.23); P = 0.20
CEE plus MPA2.05 (1.21to 3.48) P = 0.01

Abbreviations: 3MS = Modified Mini-Mental State Examination; AD = Alzheimer’s disease; CEE = conjugated equine estrogen; CI = confidence interval; HR = hazard ratio; MPA = medroxyprogesterone acetate

From: 3, Results

Cover of Preventing Alzheimer's Disease and Cognitive Decline
Preventing Alzheimer's Disease and Cognitive Decline.
Evidence Reports/Technology Assessments, No. 193.
Williams JW, Plassman BL, Burke J, et al.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.