Table 1GLD-1 mRNA targets

mRNA TargetsHomologyDevelopmental FunctionExpression MitoticExpression Early, Mid PachyteneExpression Late PachyteneExpression OocytesReferences
rme-2Yolk receptorYolk import into Developing OocytesNoNoNoYes26,57
tra-2Transmembrane receptorFemale Cell Fates in Germline and SomaN/DN/DN/DN/D28,48
mes-3Novel proteinMaternally supplied Regulator of Germline DevelopmentYesNoYesYes29
pal-1Homeodomain, Caudal orthologCell Specification in Early Embryo DevelopmentNoNoNoLimited131
glp-1Notch HomologSpecification of the Germline Proliferative Fate, as well as Cell Fates in the EmbryoYesNoNoNo30,33
cep-1p53 orthologPromotes DNA Damage-Induced ApoptosisYesNoYesYes12,58
oma-1/-2Zn-fingeroma-1 and oma-2NoNoNoYes27,34,59
(moe-1/-2)(C-x8-C-x5-C-x3-H type)Function Redundantly in Oocyte Maturation
gna-2N-acetyltransferaseMeiotic division and Early Embryonic DevelopmentNoNoNoLimited226,27,60
puf-5/-6/-7/-10PUFpuf-5 and puf-6/-7/-10 Function Redundantly during OogenesisNo3No3Yes3Yes326,33
cye-1Cyclin E homologNecessary for the G1/S-phase Transition and Centrosome DuplicationYesNoYesYes11
cej-1 (cpg-1)Chitin-binding DomainEarly embryo development, functionally redundant with cpg-2N/DN/DN/DN/D26,61
cpg-2Chitin-binding DomainEarly embryo development functionally redundant with cpg-1N/DN/DN/DN/D26,61
lin-45Raf kinaseProgression through Pachytene, Male Germ Cell FateN/DN/DN/DN/D26,37

From: C. ELEGANS STAR PROTEINS, GLD-1 AND ASD-2, REGULATE SPECIFIC RNA TARGETS TO CONTROL DEVELOPMENT

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