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Cover of Autoimmunity

Autoimmunity

From Bench to Bedside

Editors: Juan-Manuel Anaya, MD, PhD, Yehuda Shoenfeld, MD, FRCP (UK), Adriana Rojas-Villarraga, MD, Roger A. Levy, MD, PhD, and Ricard Cervera, MD, PhD, FRCP (UK).

Bogota (Colombia): El Rosario University Press; .
ISBN-13: 9789587383669 (paper)ISBN-13: 9789587383768 (digital)

This book attempts to organize the knowledge collected by those who have extensively studied autoimmune diseases (ADs) into a comprehensive overview of how the immune system, governed by its own complex yet limited pathways, turns against self targeting distinct tissues in different conditions according to a balance determined by the genetic predisposition of the host, its gender, environmental circumstances and other co-factors that modify the outcomes of a similar pathological process (…).

Contents

Juan-Manuel Anaya, MD, PhD. Director of the Center for Autoimmune Diseases Research (CREA) at the School of Medicine and Health Sciences, Universidad del Rosario, and Méderi Hospital Universitario Mayor in Bogota, Colombia. His research interests include both clinical and translational aspects of immunogenetics of autoimmune diseases. He focuses his research on the identification of common physiopathological mechanisms of these diseases. He has authored more than 200 scientific articles and served as Senior Editor of major books and journals in the field of rheumatology and autoimmunity. Professor Anaya is a member of several scientific societies including the National Academy of Medicine of Colombia.

Yehuda Shoenfeld, MD, FRCP (UK). Founder and head of the Zabludowicz Center for Autoimmune Diseases at the Sheba Medical Center, which is affiliated with the Sackler Faculty of Medicine at Tel-Aviv University in Israel. Professor Shoenfeld is the Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at Tel-Aviv University. He is also Visiting Professor at the Universidad del Rosario, in Bogota, Colombia. His clinical and scientific work focuses on autoimmune and rheumatic diseases. He has published more than 1,700 papers in the most highly reputed journals and authored and edited 25 books, some of which became cornerstones in science and clinical practice. He is on the editorial board of 43 journals in the field of rheumatology and autoimmunity and is the founder and editor of the IMAJ (Israel Medical Association Journal) as well as the founder and editor of “Autoimmunity Reviews” and Co-Editor of “Journal of Autoimmunity.” He has organized over 20 international congresses on autoimmunity. Professor Shoenfeld received the EULAR prize in 2005, the gold medal from the Slovak Society of Physicians for his contribution to Israel – Slovakia collaboration (March 2006), and the Nelson’s Prize for Humanity and Science for 2008. He has recently been awarded a Life Contribution Prize in Internal Medicine in Israel, 2012. Professor Shoenfeld has educated a long list of students who have become heads of departments and institutes.

Adriana Rojas-Villarraga, MD. Coordinator of the Center for Autoimmune Diseases Research (CREA) at the School of Medicine and Health Sciences, Universidad del Rosario, and Méderi Hospital Universitario Mayor in Bogota, Colombia. Her major areas of research are clinical manifestations and immunogenetics of autoimmune diseases as well as rheumatological musculoskeletal imagenology. She has published more than 50 scientific articles in her research fields of interest and in clinical epidemiology. Professor Rojas-Villarraga also leads the Translational Medicine Group at the CREA.

Roger A. Levy, MD, PhD. Professor of Rheumatology at The State University of Rio de Janeiro, Brazil. Professor Levy holds positions on a number of editorial boards. He has organized several international meetings. He is currently coordinating the vasculopathy committee of the Brazilian Society of Rheumatology and chaired the XIV International Antiphospholipid Congress (APLA) and the Latin American Congress of Autoimmunity (LACA) in Rio de Janeiro in 2013. His research is based on the clinical and immunological aspects of systemic lupus erythematosus, antiphospholipid syndrome, Sjögren’s syndrome, and pregnancy in rheumatic patients. He has published over 80 articles in medical journals, over 100 abstracts, and more than 20 book chapters.

Ricard Cervera, MD, PhD, FRCP (UK). Head of the Department of Autoimmune Diseases, Hospital Clínic de Barcelona, Barcelona, Spain, Director of the Research Group on Systemic Autoimmune Diseases at the Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) in Barcelona, and as Associate Professor at the Department of Medicine, Universitat de Barcelona, Barcelona, Spain. He is also Visiting Professor at the Universidad del Rosario, Bogota, Colombia. He is the coordinator of the EuroLupus Project and of the European Working Party on Systemic Lupus Erythematosus. Among other awards, he has received the Prizes of the 5th European Conference on Systemic Lupus Erythematosus, EULAR 2003, and EULAR 2005. Professor Cervera has published more than 500 scientific papers, including original articles at prestigious journals. He is the coeditor of more than 25 books on Autoimmunity and related conditions. He is also a member of the editorial boards of several medical journals. His current major research interest includes clinical and epidemiological aspects of systemic autoimmune diseases, particularly systemic lupus erythematosus and the antiphospholipid syndrome.

Supported by a grand from Colciencias (Resolución 731, Código 4101000108), Bogota, Colombia.

Center for Autoimmune Diseases Research, CREA Texts Collection, School of Medicine and Health Sciences, El Rosario University

© 2013 Editorial Universidad del Rosario

© 2013 Juan-Manuel Anaya, Yehuda Shoenfeld, Adriana Rojas-Villarraga, Roger A. Levy, Ricard Cervera.

© 2013 Alba Cristina Peñaranda, Alejandra Claudia Cherñavsky, Alejandro López, Alejandro Ruiz-Argüelles, Alexandre W S de Souza, Álvaro Arbeláez-Cortés, Ana Beatriz Santos Bacchiega, Ananías García Cardona, Andrés F. Echeverri, Ángel González, Arley Gómez López, Beatriz Aristizábal, Carlos A. Cañas, Carlos E. Toro-Gutiérrez, César Jiménez Hernández, Christopher J. Lessard, Claudia Mendoza Pinto, Dahyana Cadavid, Damaris E. Lopera H, Édgar Garavito Rodríguez, Eitan Israeli, Esperanza Ávalos-Díaz, Fabio Bonilla-Abadía, Felipe Cañas-Orduz, Gabriel J. Tobón, Gabriela Medina, Gerardo Quintana López, Gisele Zandman-Goddard, Gladis Montoya-Ortíz, Gloria Vásquez, Grégory Alfonso García Morán, Griselda Romero-Sánchez, Guilherme de Jesús, Howard Amital, Ivet Etchegaray Morales, Jaime Alberto Díaz Galvis, Jenny Amaya-Amaya, John Castiblanco, Jorge H. Izquierdo, Juan Camilo Sarmiento-Monroy, Juan Carlos Solís Poblano, Juan Castellanos-de la Hoz, Juan Manuel Pino, Juan-Sebastián Franco, León Felipe Jaramillo, Lorena Bejarano-Pineda, Luis Antonio Morales, Luis Fernando Niño, Luis J. Jara, Luisa Marina Matheus Merino, Luz Elena Cano R, Manuel J. Amador-Patarroyo, Marcela Burgos, María Teresa Bernal, María-Teresa Arango, Mario García-Carrasco, Manuella Lima Gomes Ochtrop, Mauricio Arcos-Burgos, Michael Ehrenfeld, Miguel A. Saavedra, Miri Blank, Mónica Ararat Sarria, Nazarena Ferreyra Solari, Nidia E. Correa, Nilson Ramírez de Jesús, Olga Vera- Lastra, Oscar M. Pérez-Fernández, Paola Cruz-Tapias, Paola Ximena Coral-Alvarado, Paul Alejandro Méndez Patarroyo, Paula Quintero-Ronderos, Rafael Herrera Esparza, Rafael Parra-Medina, Rubén D. Mantilla, Sandra Ramírez-Clavijo, Smadar Gertel, Socorro Méndez Martínez, Soraya Zorro, Stephanie Voorduin, Vinicius Domingues, Yiset Adriana Fernández.

© 2013 Francesco M. Marincola, MD, FACS. Preface

First Edition: Bogota D.C., September 2013

Editorial Coordination: El Rosario University Press

Proofreader: Cecile Dunn

Graphic Design: Elizabeth E. Cruz Tapias

Images: Elizabeth E. Cruz Tapias

Cover Desing: Miguel Ramírez, Kilka DG.

Special Images: The pathogenesis of the Antiphospholipid Syndrome, Bill Giannakopoulos, Steven A. Krilis, Volume No. 368. Copyright © 2013.

Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.”

Macmillan Publishers Ltd on behalf of Cancer Research UK: Nature Reviews Rheumatology, Topical and systemic medicators for the treatment of primary Sjogren’s syndrome. Copyright © 2013.

The IMGT/HLA database. Nucleic acids research. Robinson J, et al. copyright © 2013.

BMC Genomics. The human genome: a multifractal analysis. Copyright © 2011.

Macmillan Publishers Ltd. From: Raychaudhuri S, et al. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nature genetics. 44: 291–6, copyright (2012).

Impression: Imos Gráfica e Editora Ltda.

CREA

Cra. 24-63-C-69, Bogota, Colombia

+57 1 349 96 50

www.urosario.edu.co/crea

El Rosario University Press

Cra. 7 N° 12B-41, office 501 · Tel.: ++57 1 297 02 00

http://editorial.urosario.edu.co

Autoimmunity. From Bench to Bedside / Editors Juan-Manuel Anaya… [and others]; preface, Francesco M. Marincola.-- Bogota: El Rosario University Press. School of de Medicine and Health Sciences, CREA.

xiv, 856 pages: ill.—(Texts Collection)

ISBN: 978-958-738-366-9 (Paper)

ISBN: 978-958-738-376-8 (Digital)

Immunology / Molecular Biology / Tautology / Autoimmune Diseases – Diagnosis and Treatment / Clinical Laboratories / Tests Laboratory / Genetics / I. Anaya, Juan-Manuel / II. Shoenfeld, Yehuda / III. Rojas-Villarraga, Adriana / IV. Levy, Roger A. / V. Cervera, Ricard Title / VI. Marincola M., Francesco, preface / VII. Title / VIII. Series.

616.079 SCDD 20

Source Catalog – El Rosario University. Library

amv July 18, 2013

Made in Colombia

All rights reserved. No part of this publication may be reproduced without prior written permission from El Rosario University Press.

“In the end, we only have what we have given”

Isabel Allende
In “Ines of my Soul”

“Everything is autoimmune until proven otherwise”

Yehuda Shoenfeld

Image backf1.jpg

“EDITORIAL UNIVERSIDAD DEL ROSARIO” 15 años

Image backf2.jpg

This book was written in Open Sans font, size 9, it was printed on Propal paper 70 gr, and bound with Hot-Melt, on September 2013, Bogota D.C., Colombia.

This book strikes a great balance at the experimental and translational intersection in presenting cutting edge views of ADs in the broader context of autoimmunology”.

Francesco M. Marincola, MD, FACS.
[From the Preface]

The CREA Collection of “Universidad del Rosario” offers to the medical community and related areas, texts on translational autoimmunity, by which new and relevant biomedical discoveries are applied to autoimmune diseases, in their prediction, diagnosis improvement, treatment, prognosis, and prevention.

© 2013 Universidad del Rosario.
Bookshelf ID: NBK459447PMID: 29087650

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