Evidence Table 11Efficacy of oral sumatriptan -- HA relief and complete relief at 4 hrs*

ReportNo. of patients experiencing HA relief [or complete relief] @ 4 hrs withOdds ratio (95% confidence interval)
active treatmentcontrol/comparison
Sumatriptan (100 mg) vs. placebo
Cutler, Mushet, Davis, et al., 1995
#51213
N/AN/AN/A
Nappi, Sicuteri, Byrne, et al., 1994
#1960
81/114 (71%) [55/114 (48%)]24/69 (35%) [12/69 (18%)]4.6 (2.4 to 8.7) [4.4 (2.1 to 9.1)]
Oral Sumatriptan Dose-Defining Study Group [DDSG], 1991
#1280
N/AN/AN/A
Oral Sumatriptan Int'l Multiple-Dose Study Group [IMDSG], 1991
#1290
81/108 (75%) [52/108 (48%)]20/67 (30%) [9/67 (13%)]7.0 (3.6 to 14) [6.0 (2.7 to 13)]
Pini, Sternieri, Fabbri, et al., 1995
#50812
92/142 (65%) [N/A]32/80 (40%) [N/A]2.8 (1.6 to 4.9) [N/A]
Sargent, Kirchner, Davis, et al., 1995
#51240
N/AN/AN/A
Tfelt-Hansen, Henry, Mulder, et al., 1995 #53780N/AN/AN/A
Combined4.3 (2.5 to 7.5) [5.1 (2.6 to 10)]
*

Figures for complete relief in brackets

Abbreviations used in this table:

HA is headache. mg is milligram. N/A is not applicable.

From: Evidence Tables

Cover of Self-Administered Drug Treatments for Acute Migraine Headache
Self-Administered Drug Treatments for Acute Migraine Headache.
Technical Reviews, No. 2.4.
Gray RN, McCrory DC, Eberlein K, et al.

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