Table E16Cosmetic outcome

ReferenceDesign of StudyNumber of PatientsBiopsy MethodsConclusion
Krainick-Strobel et al. 200773Prospective case series of patients with benign lesions undergoing vacuum-assisted biopsy for the purpose of complete lesion removal45Hand-held ultrasound-guided vacuum-assisted CNB biopsy (Mammotome) using either an 8- or 11-gauge needle.Ninety-five percent of respondents said they would prefer CNB to open excisional biopsy if they needed a future procedure. A minimum of seven days post-procedure, patients were given a questionnaire about their experience. All patients said that the scar from the needle was cosmetically unimportant to them and, on a scale of 0–10, their mean level of satisfaction with CNB was 9.2 (range 3–10).
Weber et al. 2005502Retrospective comparison study of patients with impalpable breast lesions undergoing either Mammotome or ABBI387Stereotactically-guided vacuum-assisted CNB biopsy (Mammotome ) technique with 11-gauge needle or ABBIIncomplete satisfaction with the cosmetic result occurred at a higher rate in the ABBI group (6.7% vs. 1.3%, p = 0.03).
Wong et al. 2005171Prospective trial of Asian patients with nonpalpable mammographic abnormalities underwent either ABBI (N = 7) or Mammotome (N = 107).114CNB was performed on a prone biopsy table with vacuum-assisted CNB (Mammotome) with 8- to 11-gauge needle or ABBI.Bruising (one week post- procedure) occurred in 79 patients (46 minimal, 25 mild, 5 moderate and 3 severe) and at one-month followup a scar was visible in 79 patients (40 minimal, 32 mild, 7 moderate, 0 severe).
Mariotti et al. 2003228Retrospective study of patients undergoing either ABBI or Mammotome from June 1999-December 2001 for suspicious non palpable mammographic lesions not confirmed by ultrasonography360Vacuum-assisted CNB (Mammotome) with 11-gauge needle or ABBIBoth surgeons and patients were pleased with the cosmetic outcome.
March et al. 2003514Prospective study of women with breast masses who underwent CNB in which complete removal of the lesion was attempted.34Ultrasound-guided vacuum- assisted CNB with an 11-gauge biopsy deviceThe twenty-one subjects who did not undergo an open procedure following CNB were examined at 6 months post-CNB. Nineteen (90%) were very satisfied with appearance of biopsy area, 2 were satisfied and none were dissatisfied. Sixteen were very satisfied with how the biopsy area felt, 5 satisfied, none dissatisfied. At 6-month follow-up examination, four (19%) had no visible scar, 17 (81%) minimal scarring = 2–9 mm, none had skin retraction concavity, convexity, or other changes in breast contour.
Fine et al. 2003217Women who underwent CNB for low risk palpable masses were assessed prospectively.216Ultrasound-guided vacuum-assisted handheld biopsy device (Mammotome) with either an 8- or 11-gauge needleA majority of patients were both satisfied with the appearance of their incisions and stated that they would recommend the procedure to others in a survey conducted 10 days post-procedure (82% and 92%, respectively). By the 6-month follow-up visit, 100% were happy with the incision’s appearance and would recommend the procedure to others, while 97% stated they themselves would have the procedure again, if needed.
Kettritz et al. 2003594Retrospective analysis of patients who underwent a CNB between January 1996- June 2000 for indeterminate lesions and microcalcifications.2874Vacuum-assisted CNB on a digital prone table (Mammotest) with an 11-gauge needle.Scarring at the latest postbiopsy visit was graded as not relevant (86%), slight (14%) or relevant (0.3%).
Chun et al. 2002245Retrospective review and survey of patients who had undergone a Mammotome, ABBI or wire localized biopsy more than 2 years ago for benign disease, 20 patients per group.59Stereotactic vacuum-assisted CNB biopsy (Mammotome) with 11-gauge needle or stereotactic excisional biopsy with ABBI (15 or 20 mm cannula) or wire localized open biopsyPatients were asked to rate the appearance of their scar, if they were satisfied with the biopsy procedure, and which mattered most to them, complete lesion removal or scar appearance. Ninety-five percent of the core-needle biopsy group and only 25% of the open biopsy group were very satisfied with the appearance of their breast. None of the core-needle biopsy group said the cosmetic results were unacceptable compared to 20% of the open biopsy group who found the results unacceptable. Overall, eighty percent of subjects were more concerned with complete lesion removal than scar appearance.
Perez-Fuentes et al. 2001534Prospective case series of patients seen between August 1998-December 2000 with palpable or nonpalpable breast masses diagnosed with CNB.83Ultrasound-guided vacuum-assisted CNB (Mammotome) with 11-gauge needleNo scarring was evident at followup.
Beck et al. 2000539Retrospective review of first experience using vacuum- assisted CNB560Digital stereotaxic biopsy table and vacuum-assisted CNB (Mammotome) 11-gauge needle.In 90% no scar was visible at final followup.

CNB = Core-needle Biopsy

From: Appendix E, Evidence Tables

Cover of Comparative Effectiveness of Core-Needle and Open Surgical Biopsy for the Diagnosis of Breast Lesions
Comparative Effectiveness of Core-Needle and Open Surgical Biopsy for the Diagnosis of Breast Lesions [Internet].
Comparative Effectiveness Reviews, No. 19.
Bruening W, Schoelles K, Treadwell J, et al.

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